A swab from the nose on eosinophils and allergies: transcript
Transcript of smear from a nose Allergy
Inflammation of the nasal mucosa, swelling, reproduction transparent aconselho secret indicates a violation of the integrity of the upper and lower respiratory tract. The catalysts of irritation of the inner shell are such external factors as dust, fur of Pets, the spores of seasonal plants, tobacco smoke, household chemicals, infectious agents.
To write therapeutic regimen, it is advisable to identify the Genesis of rhinitis through research. At suspicion on allergic rhinitis, the doctor will prescribe the procedure for rhinocytogram to confirm or refute the etiology of snot.
What are eosinophils
Eosinophilic granulocytes as a subspecies of white blood cells, are present in each organism in limited quantities. They promote tissue regeneration, develop immunity against parasitic worms, exhibit phagocytic activity, slow the growth of tumors.
Immune cells are formed from the building material of the brain. The education process takes up to 4 days, after which eosinophils are outside the Central nervous system and circulate in the blood. The final stage is the localization of the granulocytes in the skin, digestive system, liver, where the duration of their life cycle varies from 8 to 12 days.
For reference! To identify the number of cells in the body it is possible on the basis of the results of the study of blood, scrapings from the nasal cavity and throat.
Specific numbers, the content of the eosinophils in the mucus does not exist, all depends on the strength of the allergen or parasitic agent. The number of blood cells varies under the influence of hormones, medication, the development of pathological processes.
Norma leukocytes in the nose of the child is measured with a unit number of neutrophils and lymphocytes, the rate of which shall not exceed 5%. If you are allergic granulocytes may in a large volume to appear in the lymph, can accumulate in miconazole mucus.
Smear Allergy of the nose
The irritation of the mucosal immune system produces secretion of protective secretions with increased or decreased concentration of white blood cells. There are several varieties of leukocytes: neutrophils are protective in bacterial lesions, lymphocytes inhibit the synthesis of viral structures of alien origin.
When sensitization to antigens on mucosal eosinophils appear.
A nasal swab for eosinophils helps to determine the etiology of the disease, stage of development and reactivity.
Indications to carrying out microscopic Cytology are patient complaints:
- disorders of the respiratory process;
- sustained release of secretions from the nose, sneezing;
- watery eyes;
Scrapings taken from the rear of the lower Department of nasal sinus, detachable paint over acidic inhibitors that affect the heterogeneity of the blackening of the photographic material. Eosinophils become red color, are available for counting under a microscope.
Fence mucus, the child requires special care not to damage the fragile epithelial layer and the blood vessels.
Steroid hormones produced by the cortex of the adrenal glands alter the concentration of eosinophils in the body. So, the day before the survey, it is advisable to limit intake of antihistamine preparations, vasoconstrictor drops.
Analyze from the nose optimally in the morning hours, when the level of the cells is reduced by 20% of the daily value.
Transcript of smear from the nose on eosinophils
The optimal number of granulocyte commensurate with their percentage to the total number of cells. The norm in children under the age of 13 in the range of 5-7% of eosinophils in adults is from 0.5 to 5%.
These indicators are considered to be the reference, because with age, the concentration of leukocyte cells growth decreases. Their content in the mucus and sputum should be minimal.
For reference! Women at the beginning of ovulation and the end of the menstrual cycle the norm of leukocytes in the blood decreases before menstruation increases.
The increase in the permissible level
When pathological changes upset the rate of eosinophils, the higher the ratio, the more serious stage of the disease. Mild percentage of immune cells reaches 10%, moderate 15%, severe – more than 15%. Increased number of eosinophils has the medical term «eosinophilia».
The analysis of the nozzle, which is marked by the increased number of granulocytic group of cells, points to pathology of allergic origin. When exposed to allergens, the immune system becomes vulnerable, the mucosa produces substances that cause Allergy symptoms.
Neutrophils in a smear from the nose with the increased number of eosinophils indicate bacterial lesions. Elevated levels may be a result of bronchial asthma, malignant tumor, the presence of worms.
Growth of cells of the leukocyte germ in infants acts as a result of prenatal infections, skin dermatitis, allergic reactions to cow’s milk.
For reference! Analysis snot administered again after 3 days. If the results are identical, it is possible to judge the validity and accuracy of the survey.
Rarely the clinical picture, eosinophilia is the cause of serious pathological disorders:
- leukemia. Hematological disease is manifested by a development of heart failure on the background of the lesion in the bone marrow granulocyte, platelet and red blood cell germs;
- periarteritis nodosa. Autoimmune process where the immune system perceives its own tissues as foreign, destroys them, resulting in necrosis of the medium muscular arteries of the type. Patients complain of fever, pain in the abdomen, kidney failure, skin rashes;
- parasitic infestations. The contamination of the patient parasitic worms of different species is active. They are introduced into the body through holistic or damaged skin.
The reason for the growth of cells of the leukocyte germ is the decrease in local immunity in intoxication, hypothermia, activation of pathogenic strains.
Interpretation of low values
The decrease of eosinophils characterized by sluggish development of pathological processes under the influence of viruses and bacteria. The absence of a smear of cells of the leukocyte germ points to the development of vasomotor rhinitis.
Against the backdrop of hypersecretion of a decrease in the number of erythrocytes, leukocytes and platelets in the nasal mucosa.
If the vitals are normal, and symptoms of rhinitis were not arrested, the formation of a secret associated with the prolonged use of vasoconstrictor drugs, hormonal changes, anatomical variations of the nasal passages, the destabilization of the emotional state of the patient.
To identify allergic or infectious nature of the inflammation of the nasal mucosa doctors prescribe rhinocytogram. Her figures are taken as the basis to develop a therapeutic scheme.
Acute respiratory viral infection, autoimmune processes, allergic manifestations, helminth infection give increase of eosinophils in the mucosa of the upper body. Lower values often indicate the progression of vasomotor rhinitis.