CA-125 when ovarian cyst: standards
Every year the diagnostic methods are improving. Blood tests now make it possible to detect faults in metabolism, and the presence of many diseases. A promising direction for diagnostics is the determination of tumor markers. This diagnostic can detect tumors at an early stage, accordingly, as early as possible to begin treatment, also helps detect the recurrence of cancer after surgery or other treatment.
If the ovaries to appear cyst, number of tumor markers CA-125 increases. Cyst – it is a benign tumor, which requires increased attention and mandatory treatment, because a high probability of conversion to malignancy. This particularly affects women who have reached menopause, then the likelihood of cancer increases.
It is important to control the content of CA 125 by passing the blood, even if it was carried out surgery to remove a cyst. This will allow time to make the necessary arrangements. What is the tumor marker CA 125? As the analysis in the ovarian cysts? What are the indicators in the ovarian cyst is the norm, and which need to sound the alarm?
What tumor markers and what are they?
Tumor markers are specific substances that appear in the blood if there cancer. When the cyst and other ovarian tumors studied tumor marker CA-125. However, this tumor marker is not specific: a few times can be increased with the presence of benign processes in the abdominal cavity such as endometriosis, uterine fibroids, colitis, ovarian cysts, etc., at the same time, many women with ovarian cancer in the early stages he should be fine. That is why determination of tumor marker CA-125 is not used to determine the tumor of the cancer prior to surgery. However, in conjunction with ultrasound, this diagnostic method is very valuable for the surgeon.
In some cases, increased the concentration of CA 125?
When blood tests for the presence of specific substances, results can be false positive and false negative. There are cases that tumor markers can be identified in the body of people who are completely healthy, or they are not diagnosed with cancer.
Increasing the concentration of the tumor marker CA 125 can be in the presence of a malignant process:
- the body, neck, mucous membrane of the uterus and also the fallopian tubes;
- the large intestine;
- the stomach;
A slight increase of this tumor marker, displaying the analysis may indicate inflammatory processes in the uterus and appendages, as well as the following diseases: pancreatitis, peritonitis, hepatitis, cirrhosis, pleurisy.
The concentration of CA 125 in the blood also increases in such diagnostic methods: analysis of smears from the vaginal and pelvic examination, colonoscopy, thoracentesis, bronchoscopy, gastroscopy, laparoscopy and computed tomography, ultrasound and radiography.
What metrics is the norm?
CA-125 is naturally present in the body of every healthy woman. These molecules in the fluid within the endometrium of the uterus. As a rule, the substance does not penetrate into the bloodstream.
Perhaps increased tumor marker CA 125 in the first days of menstruation and in first trimester of pregnancy.
Diseases of the female reproductive system such as ovarian cyst, endometriosis, infectious diseases of the pelvic organs, also provoke an increase in concentrations of CA 125, which shows the analysis.
The norm, when analysis showed the tumor marker CA 125 below 35 U/ml.
However, the results of this study can often be a false positive, i.e. malignant tumors, and yet the results are elevated.
The analysis results will be more accurate in women of retirement age.
Rules of delivery of the analysis
To determine the concentration of CA 125, it is required to draw blood from the vein. To obtain more accurate and correct result, it is necessary to observe the following rules:
- The blood test you need to pass early in the morning on an empty stomach. The last meal should be at least 8 hours before the blood donation.
- Before donating blood you can drink only water. Other drinks can affect the accuracy of the results.
- Preferably 3 days prior to collection analysis need to stop alcohol consumption and Smoking.
- Some products and dishes (fatty, fried, salty) can increase the concentration of CA-125, therefore, their use should be excluded from the diet the day before the date of analysis.
- Some medicines can change the results. We need to talk about the admission of any drug the doctor may need of its abolition at the time of analysis.
- It is not necessary to exercise and also to do massage, ultrasound and other tests a few days before analysis.
- Immediately before blood sampling need to be very calm, not nervous.
If they complied with all these points, the analysis will give the most accurate results.
The results of the survey on the CA-125 when ovarian cysts in women can decipher a doctor. It takes into account all the nuances of the clinical condition of the woman and will be able to make the correct diagnosis. Independent interpretation of results is another reason to be nervous.