Creatinine in the blood: the normal women, men, children
Creatinine is one of metabolic products, formed due to dissolution of creatinephosphate and is the end product of this process. The formation of the metabolite associated with the muscles, providing them with the necessary energy to perform the intended functions. Definitely the creatinine excreted by the kidneys, as it is harmful to the tissues of the human body connection.
For diagnosis of pathologies medical professionals determine creatinine in the blood and in the urine. This allows evaluating the mechanism of formation, revenues and excretion of metabolic product and in General to render a decision on the status creatininemia exchange. In the case of blood is usually assigned biochemical analysis.
Pathology, if you are looking for creatinine for biochemistry
Changes in which can be problems with the level of creatinine in the blood, a lot. However, frequently the increase or decrease of performance due to:
- renal pathologies;
- acromegaly and gigantism (endocrine disorders in which there is excessive growth of the extremities or whole body);
- rheumatoid arthritis;
- dehydration after vomiting and diarrhea;
- severe congestive heart failure;
- infectious diseases;
- hyperthyroidism (excessive production of thyroid hormones by the thyroid gland);
- abuse meat dishes;
- gangrene of the extremities;
- burns and muscle damage;
- leptospirosis (an acute infectious disease that primarily affects the capillaries, and then liver, kidney and muscle);
- taking a number of drugs (including antibiotics, fructose, glucose, Lidocaine, etc.);
- excessive physical stress;
- hypogonadism (dysfunction of genitals);
- the period of carrying a child (already on the second and third trimesters);
- anemia (anemia);
- muscular atrophy (a pathological decrease in muscle mass);
- the dermatomyositis (severe muscle inflammation);
- leukemia (a malignant blood disease);
- depletion of the body due to prolonged treatment or starvation.
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The normal creatinine in adults
Since creatinine is not filtered by the kidneys, its concentration in blood is relatively stable. It is worth noting that the indicators can influence gender, age, features of physical activity and diet. All these factors are considered in assessing the results of biochemical analysis of blood and in the diagnosis of the patient.
Also affect the results of mode several days before. To prevent «smearing» of values, it is necessary to adhere to the recommendations. The analysis is carried out strictly in the morning and on an empty stomach, and it is desirable to follow a diet a few days before the study. Immediately prior to this test avoid heavy muscular loads, overheating or hypothermia. It is important that the doctor strictly abide by the rules of blood sampling and was a qualified technician.
Doctors distinguish the minimum and maximum values for different groups of persons (women, men, patients older than 50 years and children). In women, the value ranges from 44 to 80 µmol per liter in men — 74 – 110, adolescents — 27 – 62, at kids — 45 – 105. In elderly patients the creatinine level slightly lower than that of younger members of the same sex.
Creatinine in women
Normal women plasma creatinine contains less than men. This is due to some physiological factors in the formation of the decay product, its distribution, circulation and excretion. More specifically, the reduced concentration of creatinine is related to the fact that women are often less engaged in physical labor, and have less muscle mass. They have a slowed metabolic processes. In addition, women’s diet has fewer meats and accordingly, exogenous creatinine.
One should not ignore the period of carrying a child. During pregnancy the body is also influenced by sex hormones, due to which the concentration of creatinine increases.
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The creatinine levels in children
Specific minimum and maximum values in this case depend more on the age of the child. The concentration of creatinine depends also on how fast the baby grows, how quickly increased his muscle mass over time. For example, in newborns, the amount of metabolite in the blood is usually not lower than in adult patients. This is due to the fact that during birth the child is experiencing significant physical exertion. The same figures are typical for adolescent children because of intensive growth. At school age the creatinine concentration is not so high and more stable.
What to do when increase or decrease of values?
If the creatinine is below normal, it does not mean any pathology and in most cases does not require any special treatment. Rather, this condition tells about a number of physiological factors. As for raising the level of creatinine, here the situation is different. It is necessary to reduce the rate. This rarely use inpatient treatment is often enough therapy in the outpatient setting.
To reduce the creatinine levels will help receive a number of drugs intended for the normalization of metabolic processes during the breakdown of proteins and eliminate toxins produced by these mechanisms. It is also necessary to regulate the water level, to avoid dehydration in the patient. To do this is to increase the number consumed per day of the liquid, be sure to view the functionality of a particular patient.
You should avoid excessive exercise, to reflect the actual ability of a person by age and sex.
Essential diet of the patient, qualitative and quantitative ratio of a number of products. You must either completely eliminate or significantly reduce the use of salts and proteins — they increase the amount of nitrogen compounds in the body and retain water, forming a swelling. In addition, protein and salty dishes increase the level of creatinine.
Remember that you evaluate the results of biochemical analysis of blood will not be able no patient. It is necessary to seek help from a qualified physician who, in addition to the evaluation of the results, prescribe appropriate treatment and offer the patient the options of prevention of creatinine in the blood.