Drugs from the pressures of the new generation: list

Hypertension continues to lead the list of the most common diseases of mankind. Simultaneously, the treatment of this disease is complicated and often requires combinations of drugs. According to statistics, only a fifth of patients with hypertension only one drug. For the rest need a combination of several means. With this purpose, the pharmaceutical companies produce a number of medicines, combining a combination of funds. In other words – a new generation of drugs.

The advantages of drugs of new generation:

  • In one pill combines several medications from different groups with different mechanism of action.
  • These drugs prolonged (long) action, so you single dose per day.
  • Patients do not get confused with pills, when and how you need to take, do not miss the drug.
  • Dose combination drugs are minimal, so the frequency of side effects is reduced.
  • A combination of drugs for high blood pressure combine such components that work synergistically with each other or mutually neutralizes side effects.
  • Bargain price – usually, a tablet of the combination drug is cheaper than some of the drugs included in the combination.
  • The list of drugs of new generation

    The combination of groups of drugs

    Active ingredients

    Pressure fell below normal?

    The Ministry of health says «a New drug normalizes blood pressure forever.»

    Trade name

    Angiotensin receptor blocker + blocker calcium





    «I have cured hypertension, You can too!»

    Actor Oleg Tabakov said


    Angiotensin receptor blocker + calcium blocker + diuretic





    Angiotensin receptor blocker + diuretic


    Valz, N




    The angiotensin-converting factor + diuretic










    Liten N

    The angiotensin-converting factor + blocker calcium



    The equator

    Beta-blockers + diuretic




    Features of some combined preparations of the new generation

  • Препараты от давления нового поколения: списокThe combination of the receptor blocker angiotensin II is valsartan and the calcium antagonist amlodipine in drug Exforge has an enhanced hypotensive effect. Each drug separately reduces the pressure are not as pronounced as in combination. The effect of the drug lasts for days, so enough single dose. When permanent or long-term use Exforge stabilization of blood pressure, the sudden cessation of the drug sharp pressure rise is not observed. In contrast to monotherapy with Amlodipine, treatment with combined drug Exforge gives a lower probability of development of edema in the patient.
  • A ternary combination of a blocker of receptors of angiotensin II, a diuretic and a calcium antagonist in the drug Co-Exforge is used to treat 2nd and 3rd degree of hypertension when monotherapy or two-component combination does not give the desired effect. A significant pressure reduction observed with continuous use of the drug for 2 weeks. Co-Exforge retains its effect during the day.
  • The drug Micardis combines a blocker of receptors of angiotensin II, telmisartan and a diuretic gidrokhlorisiazit. It is used in cases when monotherapy with these drugs no effect. Action Micardis persists more than a day, stabilize the pressure observed after a month of constant use. With the sudden cancellation of the drug the sharp rebound rise in blood pressure is not observed, the numbers return to their previous values gradually over several days.
  • ACE inhibitors and diuretic (diuretic). As you know, thiazide diuretics reduce blood volume in the vessels, but also excrete large amounts of potassium. This moment is offset by the ACE inhibitor, which retains molecules of potassium in the body. Drug Lichen N widely used in patients with combined pathology of the liver, because lisinopril is not metabolised and it does not affect the status of the hepatic cells. The researches proved the effectiveness of this combination in patients with hypertension and peptic ulcer disease. ACE inhibitors increase the secretion of mucus cells of the stomach, but also improve the local blood circulation in the body.
  • The combination of ACE inhibitor and blocker of calcium in the Equator has a mild hypotensive effect. If the patient is not taking other antihypertensive drugs, it is sufficient a single dose one tablet. If the patient takes a diuretic, it is recommended to stop taking it for a few days to the Equator or to start with half tablet of the Equator. While taking this drug should be closely monitored for water content in the body. The loss of fluids during vomiting, diarrhea or sweating may occur a significant reduction in arterial blood pressure. The same effect can be observed in the hyponatremia (low sodium in the blood). Therefore, before taking the Equator need to adjust the amount of sodium and fluid in the body of the patient.
  • The combination of beta-blockers and diuretics in Tenorite has a good antihypertensive effect, but has a number of contraindications. Patients with hypertension and diabetes mellitus are advised to monitor sugar levels on a background of reception of Tenorio. The presence of the drug a beta blocker limits its use in patients with bronhoobstrukcia, even though the dose of atenolol it. When using the drug in persons with coronary heart disease do not abruptly cancel it, as may occur with angina.
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