Drugs to lower blood pressure
The treatment of hypertension, as well as periodic reduction of the high numbers of pressure should take place under the supervision of a physician. The reception of the same drugs may have different effects on two different patients. When selecting funds, the doctor takes into account the individual characteristics of the patient’s comorbidity, the course of the underlying disease.
Principles in the treatment of hypertension
Etiotropic treatment, ie eliminating the causes of the increase in blood pressure.
Symptomatic treatment, that is aimed at the elimination of symptoms of hypertension high blood pressure, headache and heart pain, dizziness.
Classification of the means used for lowering blood pressure
Funds Central action (Clonidine, Methyldopa, Guanfacine). Has inhibitory effects on nerve centers in the brain. This leads to a decrease in the influence of stimulating pulses on the heart and blood vessels. This leads to vasodilation, reducing both the upper and lower blood pressure. Slightly eliminated tachycardia, normal pulse. Currently, because of frequent adverse reactions, these medications are rarely accepted.
ACE inhibitors (Enap, Sokaris). These drugs affect the enzyme system in the kidneys that regulate blood pressure numbers. Inhibiting angiotensin converting enzyme drugs block the chain of reactions leading to the increase in pressure. Of assets have a stable hypotensive effect and have the smallest range of adverse reactions.
Blockers (Konkor, Metoprolol). Applied strictly according to indications and prescription as they have serious side effects in the form of bronchial mast (spasm of the muscles of the bronchi), bradycardia (depression pulse), hyperglycemia (increase glucose in blood), altered mood (depression, insomnia).
Calcium antagonists or calcium channel blockers (Cinnarizine, Nifedipine). Drugs more influence on peripheral vessels, widening them. On cardiac activity is low impact. When using these drugs you need to be careful, since with increasing doses there is excessive vasodilation, which can lead to reflex stimulation of the sympathetic nervous system and reverse the increase in blood pressure.
Diuretics or diuretic (Hydrochlorothiazide, Spironolactone, Lasix). Drugs that reduce pressure by removing fluid from the body through the kidneys. When reducing the liquid portion of blood decreases the resistance in the blood vessels, which leads to a decrease of blood pressure. Drugs have adverse reactions in excretion of minerals and vitamins along with the liquid. Also, the use of diuretics increases the risk of developing diabetes and gout.
New generation drugs
Inhibitors of renin. Of the new drugs showed a good therapeutic effect is Aliseryl (Rasilez). Hypotensive effect of the drug lasts for days. It has less side effects than other drugs from the group of ACE inhibitors.
Antagonists of angiotensin II receptors. The new generation of this group include drug Olmesartan (Cardeal). At regular admission tool has a stable hypotensive effect lasting 24 hours. This effect is observed after regular use of the drug for 2 months. After discontinuation of the drugs is not observed «withdrawal symptoms».
Diuretics (diuretics). A new generation of drug is Trifas. Is long wearing, adequate intake of the drug once a day. Refers to kalisoderjasimi drugs that is does not require a restore of losses of electrolytes.
The new generation blockers (Labetalol, Carvedilol, Nebivolol). Unlike its predecessors, it is better to expand the blood vessels, reduce blood pressure and eliminate tachycardia. But, as before, this group of drugs has a strong «withdrawal».
Calcium antagonists (Amlodipine). This group of drugs is used in combination with other groups, and provides long-lasting hypotensive effect. There is a complete drug, which is composed of Amlodipine and lisinopril (Ekvator).
Simpatolitiki, antihypertensive drugs of Central action (Physiotens). In comparison with other drugs of this group, Physiotens has fewer side effects and is easily tolerated.
Drugs an ambulance, used for rapid pressure reduction
With a sharp pressure rise and the absence of tachycardia (rapid heart rate) can be taken Nifedipine under the tongue. The action of the drug starts after a few minutes of the pills. Intolerance of Nifedipine or the absence of it on hand, you can take Captopril under the tongue. The action will be late, about half an hour. If the background of hypertension, the patient has tachycardia, it is recommended to take Propranolol under the tongue. For emergency care for high numbers of pressure used intravenous magnesium sulfate, or Dibasol. Some of the recommendations in the treatment of antihypertensives:
- selection of drugs should be done only with physician;
- do not exceed the dose prescribed by your doctor;
- it is not recommended to offer your meds to another patient, as it may not be suitable;
- you should not quit the treatment without consulting a doctor;
- no need when choosing a drug guided by its price – an expensive drug does not mean effective.