Elevated blood cholesterol: what it means, what is dangerous?
The level of blood cholesterol is one of the main parameters determined in the course of biochemical studies of blood. The concentration of the substance doctors are judged on the lipid status of the person, risk his development of atherosclerosis and cardiovascular diseases, as liver. In this article, we’ll look at how to treat high cholesterol in the blood.
First of all, you should understand how cholesterol is harmful, because it is an indispensable component of cell membranes that are responsible for resistance of cells to the adverse effects. In addition, cholesterol is a precursor to many hormones and other important bioactive substances. Indeed, cholesterol cannot fully function of the body, so this substance is not harmed, his blood should not go beyond the normal scope, that is supposed to happen correct exchange.
Features of cholesterol metabolism
Cholesterol is a fatty alcohol that is insoluble in liquids. The bulk is synthesized in the human liver, and only a small part (about 20%) comes from food (fatty meat, eggs, junk food, etc.). From the liver to the tissues and back carry cholesterol lipoproteins. These complex compounds can have different density, depending on what is isolated LDL (low density lipoprotein) and HDL (high density lipoproteins). Tissue contains only about 20% of cholesterol, and the remaining part is associated with lipoproteins.
HDL collect excess cholesterol in tissues and transportyou them to the liver, where the result is a series of biochemical reactions, this fatty alcohol is converted into bile acids and bile excreted from the body through the intestines. This is why cholesterol associated with the lipoprotein of this type is considered «good». It is not deferred where it is not necessary, for example, in blood vessels.
Hypertension no longer a death sentence?
The cardiologist said that there is finally a cure for hypertension …
In turn LDL have a slightly different function. They transporterowych cholesterol from the liver to the tissues (associated with about 60% of total cholesterol in the serum). And because these lipoproteins carry cholesterol in the blood vessels in the intima which is the deposition of fat and formation of atherosclerotic plaques, the cholesterol associated with them, referred to as «bad». Therefore, when these compounds in a lot of blood, it is believed that in humans there is a very high risk of developing serious cardiovascular diseases.
If cholesterol in blood serum too much (a condition called hypercholesterolemia) and not enough «good» lipoproteins, the body cannot be cleansed of harmful excess. This means that the excess will accumulate in tissues, primarily in the intima of arterial vessels.
It is believed that safe cholesterol in the blood is considered the no more than 5.2 mmol/l For people who have problems with heart and blood vessels, this figure should be even lower. Also important prognostic significance and content of lipoproteins of different density in the blood. If a lot of cholesterol and LDL cholesterol, risk of atherosclerosis is much higher.
A condition in which can be high cholesterol:
- Inherited disorders of cholesterol metabolism.
- Pathology of the pancreas.
- Obstruction of the biliary tract.
- Improper diet, which is dominated by harmful fatty foods.
- Taking certain medicines (diuretics, hormones, antibiotics, beta-blockers, etc.).
- Diseases of the thyroid gland.
This list is incomplete. Often doctors cannot determine why the cholesterol in the blood of the patient is increased. This is called primary hypercholesterolemia that is not associated with any disease. However it found that its development is influenced by the following risk factors:
- The lack of exercise.
Thus, the blood analysis showed that blood cholesterol more than the norm. What does it mean? So it is that in the near future, a person may develop atherosclerosis (if not already) and its consequences:
I forgot about hypertension forever!
Oleg Tabakov has shared his secret to a successful struggle with high pressure.
- Coronary disease. The incidence of atherosclerosis coronary vessels (the vessels that supply blood to the heart) leads to ischaemia of the heart muscle and the most dangerous complication – myocardial infarction.
- Peripheral artery diseases. Very often, atherosclerotic changes occur in the vessels that supply blood to the lower limbs that leads to serious disorders of blood circulation and trophic tissues, and then venous ulcers and necrosis. Atherosclerosis of the arteries of the mesentery facing the death of parts of the colon, and atherosclerosis of renal artery is a serious kidney damage, etc.
- Disease of the aorta, the first aortic aneurysm (thinning and bulging of the vessel wall), at rupture which can be fatal.
- Disease of the carotid arteries supplying blood to the brain. Blockage of these vessels and atherosclerotic plaques leads to disruption of cerebral circulation and result in the development of various neurological and psychiatric disorders. In addition to the large carotid arteries atherosclerosis affects the brain arteries. The most dangerous complication of atherosclerotic lesions of these vessels is stroke, which can lead to death of the patient.
All people with hypercholesterolemia, a more detailed examination with the determination of LDL, HDL, triglycerides, and atherogenic index. The results of these analyses can be more accurately judged on the lipid status of the person, to pick up the necessary treatment, diet and give recommendations for lifestyle changes.