Eosinophils in the blood is lowered: causes
Eosinophils in human blood responsible for defense against foreign proteins (infections) and are one of the types of white blood cells. These cells continuously produce bone marrow. The life of eosinophils is small – about 3.5 hours.
Eosinophils protect the human parasites, strong allergens, they help to heal wounds. In their deficiency the body loses resistance to various diseases, an adequate immune response.
Reduced eosinophils: what does it mean?
Production of protective white blood cells – eosinophils occurs in the bone marrow of his stem cells. After their forming cells to enter the bloodstream for several hours (1 to 4 hours) sufficient to detect and «neutralize» dangerous protein compounds. After the execution of his main purpose eosinophils fall into the deep tissue of all organs, continuing his work there. The greatest concentration of protective white blood cells in areas of the body that has maximum contact with the external environment (lungs, skin, stomach, small intestines, nasopharynx).
The adult concentration of eosinophils in the blood plasma is in the range of 1 – 5% of the total weight of all leukocytes. The indicator depends on the time of day: night protective blood cells produced maximum «hunt» for viruses and bacteria. If the eosinophils in the blood is below normal, a condition doctors call eosinopenia.
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Lower bound concentrations of protective white blood cells from the child as well as adult, is 1%. However, the upper limit may increase depending on the age of the baby. Eosinopenia in children and adults is diagnosed in the case when the number of these cells becomes less than 0.5%.
The reasons for eosinopenia
Decreased eosinophils may indicate any pathological changes of internal organs and serious diseases such as:
- allergic reactions (atopic dermatitis, laryngeal edema, urticaria);
- parasites in the body (worms, Giardia opisthorchis, roundworm);
- sepsis in adults, toddlers and infants also can cause a decrease in the level of eosinophils in the blood plasma;
- down syndrome in children;
- the postoperative period after major surgical interventions.
- prolonged inflammation of chronic nature;
- burns, covering 30 percent or more of the skin of the patient;
- the initial stage of serious communicable diseases, the recovery period after them;
- severe intoxication of the organism;
- typhoid fever.
- painful shock;
- strong stressful situations;
- chronic lack of sleep;
- after a course of taking certain drugs (anticancer drugs, antibacterial agents, corticosteroids, chemotherapy drugs, etc.);
- during pregnancy in women;
- severe mechanical trauma of the abdomen and thorax;
- after a strong physical exertion;
- severe poisoning;
- myocardial infarction (fall of eosinophils occurs in the first couple of days after the rupture of the heart muscle).
To confirm the diagnosis and correct selection of methods of treatment the patient must undergo the following tests:
- urinalysis and blood;
- blood biochemistry;
- Ultrasound of all abdominal organs (especially kidneys and liver);
- thyroid hormones;
- analysis to identify hepatitis;
- the bacteriological sowing.
A blood test for eosinophils
How to prepare for the delivery of this analysis?
- to donate blood from a finger on a completely empty stomach (may drink water);
- two days before the surrender is prohibited to eat fatty foods, Smoking and drinking alcoholic beverages;
- a couple of days before delivery of the biomaterial should avoid strong stress and anxiety.
Attention! Failure to follow any of these rules may lead to distortion of the result of the analysis. You must inform the technician during the blood collection.
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In some cases, the doctor will refer to the blood test for eosinophils?
Indications for blood from the finger for the diagnosis of eosinopenia are:
- bronchial asthma;
- hay fever;
- urticaria and other types of allergic reactions;
- detection of parasites in the body (opisthorchis, intestinal worms, Giardia, etc.);
- with exacerbations of chronic infectious diseases;
- with intense inflammatory processes in the body accompanied by large Department pus;
- systemic blood diseases (scleroderma, systemic lupus erythematosus);
- disease of bone and connective tissues (arthrosis, arthritis, periarthritis);
- disrupted the formation of blood (leukemia, Hodgkin’s disease);
- skin diseases (psoriasis, eczema, pemphigus, some varieties of cutaneous zoster).
Eosinopenia during pregnancy
The majority of pregnant women, the level of protective white blood cells is kept slightly below normal for the entire period of gestation. During the generic attempts of the body experiences severe stress, severe pain, so at birth there is an absolute eosinopenia in 99% of cases. Age newborn to two-week figure of eosinophils mom will be back to normal.
A specific method of enhancing the protective white blood cells in the blood serum is not yet invented. You can only cure the underlying cause of this symptom (infectious disease, etc.). In cases where eosinopenia caused by an elementary lack of sleep or chronic fatigue, the patient is recommended to just have a good rest for a few days to come back to normal.