Lymphedema of the lower extremities: medical treatment
Lymphostasis of lower extremities is a disease of the lymph nodes, which is based on the stagnation of venous blood, particularly in the lower extremities. Pathology is manifested by edema, heavy legs and pain. In the absence of treatment and the progression of the disease goes into lymphostasis elephantiasis, which leads to patient disability.
Drug treatment of the disease does not remove all symptoms, is one of the points of combination therapy. In combination with other treatment methods medications reduce the risk of developing elephantiasis and other complications of lymphedema.
Group of drugs for the treatment of lymphostasis of lower extremities
Venotonic is the drug, mechanism of action which is aimed at improving the tone of veins. Drugs able to selectively accumulate in the veins, reducing the extensibility of their walls, increasing their tone and as a result, reducing swelling in the lower extremities. In addition, venotonic increase the tone of the lymphatic vessels to increase the strength and frequency of contractions of the vessels of the lymphatic system. All this leads to improvement of microcirculation in the lower extremities, increases the amount of oxygen and nutrients available for tissues. In addition, venotonic increase the protective properties of the capillaries, white blood cells less «attack» damaged blood vessels, which leads to reduction of the inflammatory process in the tissues of the lower extremities. To venotonic include drugs such as Phlebodia, Detralex, Troxerutin (tablets and gel), Venerus and Venodiol. The minimum course of treatment onotonicity – month courses it is better to repeat 2 – 3 times a year.
Venotonic of plant origin. All the above properties, and herbal preparations based on horse chestnut. These include Naphazoline, Vineplant, Escin and Venastat. Drugs are produced in the form of tablets, drops for oral administration, gel or cream for external use. You can combine taking the drug orally and topical treatment.
Angioprotectors are drugs that have a protective effect against the vascular wall. They increase the resistance of the endothelium (inside blood vessels) to the action of damaging factors, reduce capillary permeability to toxins and harmful substances that increase the elasticity of blood vessels, thereby reducing their fragility. In short, drugs are protected vessels. This group of drugs includes the Vitamins, Trental, Chimes, Venitan, Actovegin, L-lysine aescinat. Plant angioprotectors are medicines based on Ginkgo biloba – Bilobil, Ginkgo Biloba, Tanakan. In addition to the above properties, these drugs have a vasodilating action, improves tissue nutrition and promotes oxygenation and is a good prevention of venous complications of lymphedema.
Enzyme preparations (Wobenzym) is a comprehensive drugs that have antiplatelet (anti-clotting), anti-edematous, anti-inflammatory, immunostimulatory, and fibrinolytic (dissolution of blood clots) action. While the use of Wobenzyme with onotonicity and angioprotectors increases the action of the latter.
Homeopathic remedies (Lymphomyosot). The drug has a lymphatic drainage action, i.e. accelerates the movement of lymph through the vessels. Appoint him after the course of angioprotectors, when the vessel wall is enhanced. If the flow of lymph to strengthen, subject to weak vascular walls, this can lead to the opposite effect and increase swelling. Lymphomyosot begins to act immediately, but after the accumulation of therapeutic doses in the body. Therefore, take this drug you need at least a month, and preferably 3 to 6 months. Available in solution for parenteral (intramuscular, subcutaneous injection), drops and tablets for oral administration.
Antiplatelet agents (Aspirin, Cardoral, Trental) prevent the agglutination of erythrocytes and platelets with each other and, accordingly, provide an obstacle to the formation of blood clots. Assigned these drugs for prevention of thrombotic complications of lymphedema.
Diuretics (Lasix, Torasemid) is drugs in ambulance, used with great caution and only on prescription. After taking these drugs derived from the body plenty of fluids. To make up for losses of fluid from the tissue begins to actively move in the bloodstream, swelling in the legs decrease, but not for long.
Antibacterial agents are appointed in infectious complications of lymphedema or to prevent them. The most common organism causing infection of venous leg ulcers is Staphylococcus aureus, which is sensitive to penicillin range of antibiotics. This group of drugs and is prescribed (Ampicillin, bicillin 5).
It must be remembered that medication is only one of the points of the complex treatment. Medications will have a greater effect in combination with other methods – physical therapy, compression bandages, physiotherapy, lymphatic drainage massage and diet.
With the ineffectiveness of conservative treatment, the progression of swelling and the formation of lymph bags or foci of fibrosis prescribe surgical treatment of lymphedema.
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