Monocytes are elevated in a child: causes

A blood test, if it seriously can give a complete picture of the condition of the body, including children. The change of blood parameters, as upward and downward, may indicate a pathological process. Knowing this, delivered on time a blood test will help prevent dangerous complications or life-threatening condition. Therefore, for the prevention pediatricians recommend at least once a year to take a blood test the children, and in every case of the disease.

Monocytes, for which they need child?

Each of the blood components (erythrocytes, leukocytes, monocytes, eosinophils and others) performs a specific function in the body, and sometimes several functions. Here and monocytes play an important role in child protection. In contact with any foreign material in the body of the baby begin to work monocytes. So, their functions can be divided into several areas:

  • Participates in cellular immunity. They are struggling with any infection (viruses, bacteria, fungi), toxins, dying cells, toxins and tumor cells.
  • After the inflammatory process in the lesions remain dead cells (bacteria and leukocytes), toxins, products of disintegration of tissues. Monocytes act as cleaners and remove from this center all of these components. They also prepare the site of inflammation to regeneration (restoration).
  • Protection of healthy tissue from inflamed. Monocytes are surrounded by an inflammation, creating a protective shaft. All of this prevents the spread of inflammation throughout the body. The same thing happens during the destruction of a foreign body because it is surrounded by a protective layer of monocytes.

What is monocytosis in a child?

Each of the blood parameters have their reference values, i.e. the boundaries of the norm, outside of which develops pathology. So, elevated monocytes in the blood is called monocytosis, low – monomania. We must distinguish between the absolute value of monocytes in the printout of the analysis referred to as «abs», and relative value. The absolute indicator is the number of monocytes in the range from 0.7×109/L. the Excess of these figures suggests that one should look for the cause that may be hiding serious diseases that threaten the child’s life. A relative monocytosis is an option exceed the number of monocytes relative to other leukocytes, occurs when the decrease in the number of other cells – lymphocytes, neutrophils. The relative number of cells expressed as the percentage of the sum of all white cells must be 100%.
Моноциты у ребенка повышены: причины
A relative measure of monocytes dependent on the age of the patient. So, for newborns, the figure is normal in up to 12%, in infants this rate is reduced to 10% in adolescents to 9%, in adults these cells should not be more than 8% relative to all leukocytes.

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The increase of monocytes, why this is happening?

Causes of monocytosis are their basic functions. Any protective process in the body of the child will lead to an increase in the number of these cells. It should be noted that the limit of monocytes is not a disaster, but a signal that the immune system and the body with something struggling. And if the external manifestations of this struggle yet, it is the best time to examine a patient and find the pathological process.

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  • Infectious and parasitic diseases (malaria, toxoplasmosis, infectious mononucleosis, brucellosis, syphilis, ascariasis).
  • State after infection.
  • Diseases of the blood (Hodgkin’s disease, myeloid leukemia).
  • Autoimmune (systemic) disease, when the body’s own cells perceived as foreign (systemic lupus erythematosus, rheumatoid arthritis).
  • Inflammatory diseases of the gastrointestinal tract (ulcerative colitis, enteritis).
  • Conditions after surgeries (e.g., removal of adenoids, tonsils, Appendix).
  • Poisoning by some substances (phosphorus, tetrachlorethane).
  • Sometimes infants monocytosis may be accompanied by physiological inflammatory process in dentali (tooth eruption), in older children – when the change of teeth (loss of milk).

    What if monocytes in the blood exceeds the norm?

    Monocytosis may be detected accidentally during routine examination of the child. In this case, the question arises, whom to contact and what to do next. If parents do not have any complaints to child should visit the pediatrician. He will examine the child and, if necessary, appoint additional examination. If it turns out that the child’s teeth erupt, or it has recently suffered an acute viral, bacterial or fungal infection, is to do nothing, monocytosis soon will pass by itself. If no visible pathological changes are found, the child will be carefully examined. There are several options for examination of children with monocytosis:

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    Моноциты у ребенка повышены: причины

  • If you suspect the infectious nature of monocytosis child will be examined by the infectious disease. In the presence of complaints of vomiting, diarrhea will need to pass a stool on the intestinal group, the sowing of vomit to determine the nature of the infection that caused the disease.
  • If no complaints, conducted an ultrasound of the abdomen (to exclude inflammatory diseases of the digestive tract), urinalysis (to exclude inflammation in the genitourinary system), the analysis of a feces on eggs of worms (to avoid parasites), give up serological tests to exclude rare infections (malaria, syphilis, brucellosis and other).
  • If the child on the background of monocytosis enlarged lymph nodes, you need to test your blood for the presence of atypical mononuclear cells (to rule out infectious mononucleosis), you must retake the blood test and to hold a bone marrow puncture to exclude leukemia (blood cancer), Hodgkin’s disease.
  • In the presence of complaints of pain in the joints, changes of the heart (noise auscultation) is required to conduct a survey on autoimmune diseases. To test for rheumatology test (C-reactive protein, seromucoid, etc.), to show the child the cardiorheumatologists.
  • Monocytosis and abdominal pain is reason to visit a pediatric surgeon, as the combination of these symptoms can be a sign of incipient appendicitis, colitis, enteritis, peptic ulcer and others.
  • If the child coughs for more than two weeks, and the blood is determined by absolute monocytosis, that would be a mandatory consultation of the phthisiatrician. This syndrome can be the consequence of tuberculosis. This is a rare but possible option. In this case, children up to 15 years to hold the General examination (clinical blood analysis, General urine analysis, conduct a diagnostic Mantoux test, provide fluorogram parents). Children over 15 years old are allowed to conduct x-ray examination of the lungs.
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    Treatment of monocytosis is the elimination of the causes that caused it. Exceeding the normal values of monocytes is a signal that the body is inflammatory or other pathological process.