Reduced monocytes: causes
Although it is common knowledge that to properly «read» the results of the blood test will only be qualified, some of the patients are interested in knowing what show certain results. An important indicator is the level of monocytes. These cells are a type of white blood cells and are responsible for the absorption of microparticles (bacteria and fungi). A condition in which the number of monocytes is reduced, is called monocytopenia.
The rate of monocytes in the blood
The level of monocytes depends on the age and, oddly enough, from the nationality of the person (although in this case the differences are not too great). So, in the adult, the normal number of these blood cells is 3 to 11% of the total number of leukocytes (approximately 450 units per 1 ml of blood), and the child — 2 – 7%. Doctors often use absolute indicator of monocytes. For the adult it is approximately 0,04х109/L. in children the figure «jumps» in the growth and development that is the norm. Usually permitted reduction in monocytes 10%, depending on age.
Why can be reduced monocytes in adults?
On monocytopenia say, when the percentage of monocytes drops below 1% of the total number of leukocytes. This condition may be typical for physiological processes (e.g. after prolonged fasting), and for a number of diseases of different organ systems.
Consider a variant of the norm. The figure falls, if one long fast or eats properly, does not follow a balanced diet. The same can be said about the depletion of the body due to excessive exercise, stress and other emotional overloads, recent surgery or prolonged illness.
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In addition, the result can affect the labors and pregnancy (in some cases; monocytopenia long-term negative impact on the fetus and the process of carrying a child) and administration of various drugs (most often we are talking about corticosteroids). Improper prep can also «lubricate» the picture, so be sure to consult with your doctor about the need for special events before diagnosis.
With regard to pathologies, here is a list of possible options is significantly wider. The level of monocytes clearly reflects the effect of cancer, purulent, or infectious processes in the body, so the figure could be reduced if:
- Progression of acute or severe infectious disease in which the leukocyte count in General decreases — these include, for example, typhoid fever.
- Oncology and the effects of her treatment — after chemotherapy, ionizing radiation, etc.
- Poisoning by chemicals.
- The presence of severe purulent processes in the body.
- Anemia, especially those species that are associated with abnormalities of the bone marrow — the hematopoietic organ.
- Pancytopenia is also a disease of the bone marrow, but in this case, the problem occurs with the production of all blood cells: red blood cells, platelets, and leukocytes.
There are also situations when monocytes are not in the results, and their rate is «0». This shows about dangerous abnormalities in the body. These include sepsis (popularly referred to as «blood poisoning») and severe leukemia. In the first case, the number of cells is just not enough to cleanse the body and cells are destroyed due to toxins of the pathogen. The second situation is characterized by the fact that the development of monocytes terminated at all, which detect the cells in the analysis is not possible.
Reduced monocytes in a child: causes
Overall, the reasons for which the figure of the child is reduced, do not differ from those of adults. The only difference is that for children possible large jumps in the level of monocytes due to the processes of growth and development. About which indicators are the norm for your child, consult your pediatrician.
In addition, children are more exposed to various injuries and microorganisms, which are more likely to suffer from monocytopenia. Remember, that approximately in 95% of cases a decrease in the level of monocytes is associated with activity of parasitic organisms — bacteria and fungi.
How to treat monocytopenia?
The very state of decline in monocytes not treated. It is important to diagnose the underlying cause and start to deal with it. If the issue is the activity of the parasites, then will be prescribed a course of appropriate antibiotics. In the case of diseases of the blood and organs of hematopoiesis, the treatment process will be longer and more severe.
Defining the causes of monocytopenia and its treatment should only by a qualified doctor so as to get rid of the problem «at home» not only fails, it also can be dangerous. Do not self-medicate!
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