The average volume of a red blood cell: what is it?
Mean corpuscular volume is a part of clinical blood analysis. In the world there is a common abbreviation for this metric is the MCV that indicates the average volume of the blood component, in this case of the erythrocyte. With the help of analysis you can set the number of these particles and their volume and to estimate the dimensional parameters of the element.
In some cases, the results are uninformative, because the formula of the blood is rejected due to certain reasons. For example, if you changed the size anisocytosis blood cells, and the poikilocytosis – shape. Such deviations do not give the opportunity to fully and reliably perform analysis. Erythrocytes – the most important blood components. They participate in many physiological processes:
- carry oxygen and carbon dioxide, thereby participating in the breath;
- transporterowych selected by the body amino acids and fats to the tissues, nourishing them;
- carry enzymes;
- regulate the balance of acid and alkali;
- remove toxins;
- participate in fibrinolizina determine the constancy of the blood indicators.
Why do you need to know the increased MCV?
The main purpose of this study is identification of problems of blood, because at MCV you can learn a hematological pathology. They often resort to the analysis in the case of pre-diagnosed anemia, to confirm or refute the presence of the disease. The analysis also helps to diagnose microcitarnaya to the problem of acute shortage of iron.
When deficiency of cyanocobalamin analysis may indicate macrocytic anemia.
In addition to violations of anemic type, the results of the analysis demonstrate the features of water-electrolyte constancy. This is very important, especially if the problem lies in the intracellular intravascular or sector. With increasing average volume of the erythrocyte hypotonic suspected violations, while reducing normal – dehydrated.
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The procedure of taking analysis
Analysis of the MCV is not any specific procedure. It is held as part of the clinical blood analysis. Analysis requirements of the standard. The patient needs to donate blood in the morning, preferably before eleven o’clock. The procedure is performed on an empty stomach; better if will be no heavy physical exertion and emotional stress before the procedure. Blood is almost always taken from a vein, but sometimes you need a fence of arterial blood.
The definition of the indicator
MCV is measured in two units – cubic micrometers and femtolitre. The latter parameter was used in the Netherlands for the measurement of liquids containing alcohol, now the measurement femtolitre successfully applied in the determination of blood parameters.
The method of determining MCV is the passage of blood cells through a special slightest hole geoanalyzer. At the end of the analyzer can be seen as distributed red blood cells in total blood volume. A numeric score is calculated by the following formula: hematocrit multiplied by ten and divided by the number of red blood cells multiplied by ten to the sixth power.
The norm of the index in different age groups
The standard value is adopted as the norm, is from eighty to one hundred femtoliters. If erythrocytes are placed in the amplitude, they are normocitov promoted suffer. The figure below eighty – microtic, and above a hundred – macroset. Mean corpuscular volume may change throughout a person’s life. Newborns have a record of about one hundred and twenty-eight, but soon, mean corpuscular volume comes back to normal. At the age of one year, the rate drops slightly below normal – about seventy five to seventy seven femtolitre, but in five years he again reaches normal.
MCV is not the same in women and men, but a big difference in these indicators are not present, they invested in the norm of 80 to 100. If the aim is to clarify the type of anemia, when determining the average volume of a red blood cell is counted and the color index, and hemoglobin content. With decreasing intensity of color paint blood suspect the decrease in hemoglobin level or the oversaturation of the body with lead. With brighter coloring can be suspected deficiency in folic acid. Interpretation of results the analysis is carried out by a medical specialist.
Causes of low average volume of erythrocytes
If the laboratory tests show a decrease in the index, the doctor may suspect a violation of water-electrolyte balance, which in turn says about the dehydration. In this case the body lacks of fluid, and, therefore, reduced and mean corpuscular volume.
Decreasing evidence of hypochromic and microcytic anemia is triggered by disruption in the production of hemoglobin. It is known that hemoglobin has an impact on the size and shape of the erythrocyte. If hemoglobin in the blood is insufficient, the red blood cells will be significantly smaller. This analysis helps to identify very severe pathologies associated with problems of synthesis of hemoglobin in the body – thalassemia.
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Causes increases in blood
If mean corpuscular volume is elevated, this indicates a lack of vitamin B12. In this case, the proportion of red blood cells decreases, but they become a giant by their standards of the form. A slight deviation from the norm in the direction of increase can be caused by Smoking, hormonal contraceptives, alcoholism.
Interestingly, alcoholism hemoglobin in these patients is in the normal range, but blood tests diagnosed with macrocytosis. This figure can return to normal, if within three months not to consume alcoholic beverages. Also mean corpuscular volume rises in diseases of the bone marrow, pathology of the liver and disruption in the endocrine system.