Total bilirubin: normal women in the blood

Determination of the amount of total bilirubin and its fractions, it is very important to assess the General condition of the woman’s body for control over its liver. Additionally, these numbers can reveal such serious diseases as cirrhosis, liver cancer, hemolytic disease, and others. With increasing levels of bilirubin can be time to suspect the disease and prevent threatening consequences. So carrying out biochemical blood analysis is recommended for all women once a year, and in the presence of complaints on a quarterly basis.

What is the total bilirubin?

This is a special pigment in the human body resulting from the decay of hemoglobin. This decay occurs in the cells of the so-called reticuloendothelial system, the major organs which are the liver and spleen. That is why the bilirubin is part of bile, and the amount in the blood reflects the functional state of the liver. There are two types of this pigment:

  • indirect (free), which is quite toxic to humans;
  • direct bilirubin (linked, conjugated) is neutralized special proteins of the liver pigment, in this form it enters into the bile, then into the intestinal lumen and excreted together with feces.

When working properly, the liver cells is hampered by the linking process is indirect bilirubin, which is toxic to the body and can lead to various pathologies. When carrying out biochemical blood analysis considers the content of direct, indirect fraction, and the amount of turns total bilirubin.

How to determine the amount of bilirubin in the blood of women?

This is done by a special biochemical blood analysis. To obtain reliable result of the analysis should respect some requirements:

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  • Blood need to take on an empty stomach. Valid not to eat 4 hours before analysis, but it is better to endure a period of 12 hours.
  • Before blood delivery it is not recommended to take fatty foods and sweets. Better to have dinner a light dinner (vegetables, fruits, dairy products). To starve or follow a strict diet before the examination is also desirable.
  • It is not recommended to drink soft drinks (strong tea, coffee and alcohol) before analysis.
  • Reception choleretic drugs, enzymes, medications, or blood thinners, it is better to temporarily stop, but before doing this be sure to consult with your doctor.

The rate of bilirubin in the blood of women

Given that the amount of hemoglobin in blood of women less than men, and the level of total bilirubin is different. Rate the content of this pigment within a woman’s life is almost the same and is about 5 – 21 µmol/l, it differs only in the neonatal period girls. Sometimes these figures can vary depending on physiological processes. Thus, during the ovulation rate of bilirubin can be reduced to 5 – 15 µmol/L. Also these boundaries decreases with a sharp change of climate or hypothermia women.
Общий билирубин: норма у женщин в крови
It should also be noted that the amount of direct bilirubin should not exceed 25% of the total number. While the number of indirect bilirubin should be less than 75% of the total.

The normal total bilirubin in women. Table age

The age of the woman

The rate of bilirubin

Baby girl 1st day life

Not more than 35 µmol/l

2 day life of girls

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25 – 150 umol/l

3 – 5 day of life girls

25 – 205 µmol/l

From the 5th day of life up to 60 years

5 – 21 µmol/l

60 – 90 years of a woman’s life

3 – 18 umol/l

Women over the age of 90

3 – 15 umol/l

When an increased amount of total bilirubin?

  • Diseases of the parenchyma (cells) of the liver. Impairment of the function of the liver cells or their destruction leads to increased amount of bilirubin. It occurs in viral or toxic hepatitis, hemochromatosis, congenital syndromes, Gilbert, alcoholic steatosis, or cirrhosis.
  • Diseases of the biliary tract, when there is a stagnation of bile. Bilirubin in this case, enters the bloodstream, not the intestines. This happens cholelithiasis (obstructive jaundice) during pregnancy sklerosiruuschem cholangitis (inflammation of bile ducts), biliary cirrhosis.
  • Hemolytic disease or hemolytic anemia, when red blood cells are destroyed in large numbers and early. The liver can not cope with this load, bilirubin did not have time to conjugialis, and its number increases.
  • Pernicious or b-12 deficient anemia.
  • Infectious disease (sepsis, syphilis, typhoid, pneumonia, infectious mononucleosis, cytomegalovirus infection, helminthiasis), when toxins have a toxic effect on the liver reducing its functions.
  • Cancers and tumors often metastasize to the liver, which reduce or stop its function.
  • In some cases, reduced the number of total bilirubin?

  • Depression. Almost 90% of cases there is a reduction of pigment in this pathology. This is probably due to inhibition of all metabolic processes in a woman’s body.
  • The TB infection.
  • Coronary heart disease.
  • Carcinoma of the liver.
  • What are the dangers of increased levels of bilirubin in the blood for women?

    Due to its lipophilicity (lipid solubility) bilirubin if elevated levels are well associated with the structures of the skin, causing jaundice, and also penetrates the blood-brain barrier, disrupting the function of brain tissue. The latter option may cause nuclear jaundice, hepatic encephalopathy and impairment of body functions. If you raise the level of bilirubin 170 µmol/l may develop renal or cardiovascular insufficiency, and excess rate of more than 300 µmol/l can lead to death of the patient.