Treatment of trophic ulcers of the lower limbs: drugs

Leg ulcers that have formed as a result of malnutrition and oxygen starvation of the tissues, are called trophic. Basically they have some reasons.

Among them are:

  • vascular factors (atherosclerosis, hypertension, thrombophlebitis);
  • infectious agents (syphilis, erysipelas, tuberculosis);
  • injuries, frostbite, burns;
  • diabetes.

Therefore, for successful treatment it is necessary to eliminate the causative factor, and, in parallel, to reduce the unpleasant symptoms local treatment. With the treatment of this pathology the delay is not worth it, because it often leads to life-threatening complications.

The stages of treatment of the disease

  • Surgical treatment is indicated only in cases of extensive tissue damage, infection, wound infection and the threat of its spread throughout the body.
  • Drug treatment is aimed at reducing inflammation in the tissues, the vessels expand, improving blood flow and lymphatic drainage, reducing swelling of tissues. Used as taking the drug orally or topical treatment of ulcers. This can be attributed to and physical therapy the ulcerous surface.
  • Treatment of the underlying disease, which led to the emergence of trophic ulcers on the legs. Without completing this stage, complete healing is impossible and may lead to recurrence of ulcers.
  • Drug treatment of trophic ulcers of the lower extremities, General principles

    Treatment with drugs necessarily accompanies and complements surgical methods for the treatment of ulcers. No matter what is the cause of sores, there are some General principles of its treatment.

    Pressure fell below normal?

    The Ministry of health says «a New drug normalizes blood pressure forever.»

    • Antibacterial drugs. To prevent the accession of secondary infection (as the ulcer is an open wound and, in fact, the entrance gate for bacteria), antibiotics with wide spectrum of action. These include macrolides (Azithromycin, Sumamed, Klacid), aminoglycosides (Amikacin), cephalosporins (Emcef, Cefutil), antimicrobials (Chloramphenicol). Prescribers course at least 10 days, often intramuscularly or intravenously.
    • Anti-inflammatory drugs non-steroidal group. Trophic ulcers are widely applied diclofenac (Voltaren, Ibuprofen), nimesulide (Nimesil). Medications shown if the patient has no chronic inflammatory diseases of digestive tract (peptic ulcer, or colitis) or no cases of stomach bleeding.
    • Лечение трофических язв нижних конечностей: препараты

    • Antithrombotic drugs (antiplatelet agents). Given that trophic ulcer often formed on the background of thrombophlebitis (inflammation of the venous wall), and also that ulcer increases the likelihood of blood clots are drugs that thin the blood and dissolve blood clots. These include Reopoligljukin, Pentoxifylline, Trental and ascorbic acid.
    • Desensitizing (anti-allergic) drugs are prescribed to reduce the response inflammatory response. Apply Tavegil, Suprastin, Eden, claritin and others.
    READ  Atherosclerotic heart disease

    The treatment of trophic ulcers local media

    Local treatment aims to remove the dead top layer of skin (epithelium), cleansing the wound of infection and the acceleration of epithelialization of the wound. With this purpose, first wash the wound with local antiseptic (disinfectant), and then apply a bandage with antibacterial ointment. Antiseptics, which are used today: Chlorhexidine, Miramistin, Furacillin, Deksan. Ointments are preferred: nasal spray, Ofloxacin, Toxicol.

    In that case, when the process of ulcer healing (stage 2 treatment), appointed by the ointment, promotes the formation of epithelium. These include Solcoseryl and Actovegin. Also added drugs, antioxidant (Tocopherol, for example).

    The treatment of ulcers of the lower extremities depending on their causes

  • Arterial trophic ulcers. The basis of their occurrence is the deposition of cholesterol plaques on the walls of the arteries and development of atherosclerosis. As a result, the blood vessels constrict in the lumen, blood flows to the tissues in smaller quantities, occurs hypoxia, and then necrosis. Accordingly, treatment will be aimed at reducing the content of cholesterol in the blood (diet, administration of statins).
  • Venous ulcers when their appearance cited a violation of the venous outflow of blood from the lower extremities. In particular, this happens when varicose veins. For the treatment of this disease use the so-called phlebotonics, strengthen venous tone (Detralex, Venoruton), anticoagulants (Heparin, Fraxiparine, Aspirin), anticoagulants (Tocopherol). Also use a compression bandage. They also help in the treatment of varicose veins and ulcers, improving lymph flow, venous blood flow and reducing tissue swelling.
  • Diabetic trophic ulcer is one of the complications of diabetes. The high content of sugar in the blood hinders wound healing, such ulcers for a very long time to heal. However, the patient should carefully follow all recommendations of doctors and to prevent the increase of glucose level in the blood. With this goal in type 1 diabetes are using insulin, in type 2 – glucose-lowering pills. Such ulcers very often complicated with gangrene, some patients have to amputate the limb.
  • Hypertensive ulcers, occur on the background of arterial hypertension. It is a rare species of ulcers, occurs more frequently in the female half of the population. Treated underlying disease hypotonic agents (beta-blockers, calcium antagonists, diuretics and others). The scheme of treatment is chosen only by the doctor for each patient individually.