Antihistamines in urticaria: how to apply?

Hello, dear readers. The treatment of such diseases as urticaria depends on its forms and causes.

Therapies at the same time, are basically similar and consist in the diagnosis, avoiding contact with the allergen, the identification of causes of illness and pharmaceutical treatment, in particular using antihistamines.

What are antihistamine?

Антигистаминные препараты при крапивнице: как правильно применять?The antihistamine is a medicine that blocks the histamine system and slowing down the negative allergic reactions that manifest on the skin.

Antihistamines in urticaria prescribing doctor, regardless of the reasons and stage of the disease.

These medications are typically applied using cosmetic products (gels, ointments, creams), corticosteroids and other therapies.

Types of antihistamines used in urticaria

Presented to a group of medicines available in the form of tablets, sprays, ointments, injections, drops. The most popular are pills and ointments for local use.

Currently, with the symptoms of urticaria prescribers, including blockers of H1 receptors.

There are four generations represented antihistamine. Consider in more detail their names, efficacy, contraindications and demonstrate some of their pictures.

Antihistamines first-generation

Антигистаминные препараты при крапивнице: как правильно применять?These drugs have a fairly low cost, despite high efficiency. They are prescribed usually to treat hives simple form in adult patients.

They have quite an extensive list of contraindications and side effects, among which drowsiness, mydriasis, decreased vitality, blurred vision, dry mouth.

In addition to this improvement, the patient observed a very long (up to 8 hours). The most common medications of the first generation is:

  • Suprastin;
  • Diphenhydramine;
  • Tavegil;
  • The pain;
  • Peritol;
  • Fenkarol;
  • Pipolfen.

Drugs of the second generation

Антигистаминные препараты при крапивнице: как правильно применять?These medicines are nesuderinami. In addition, the list of side effects is lower than the first generation.

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After receiving no sleepiness and reduced brain activity. They are often prescribed for skin irritation and severe allergic reactions.

The most popular are:

  • Zodak;
  • Claritin;
  • Was trexel;
  • Fenistil;
  • Semprex;
  • Gitalong.

These medications are contraindicated for people with diseases of the cardiovascular system, as have her negative cardiotoxic effect. Some of them are available in the form of a gel that allows the local level to deal with the rash.

Drugs of the third generation

Антигистаминные препараты при крапивнице: как правильно применять?They are the active metabolites. They have excellent anti-allergic properties as well as the minimum set of contraindications and side effects.

Today it is the most modern and, according to reviews of patients with urticaria and effective medications:

  • Effective;
  • Zyrtec;
  • Telfast.

They can be used for the treatment of acute and chronic urticaria, in adults and children (in particular Zyrtec manufactured in the drops).

Drugs 4th generation

Recently, experts have developed new medications anti-allergic nature. They differ from all the previous fast effects and also long-lasting effect.

Антигистаминные препараты при крапивнице: как правильно применять?They permanently block the H1 receptors, thus eliminating almost all the symptoms of hives and other rashes.

As significant advantage is absence of harm to the cardiovascular system, so they are safe enough.

Despite this, there are a number of contraindications, which include pregnancy, children, lactation. The list of drugs 4th generation is:

  • Aerius;
  • Xyzal;
  • Cetirizine;
  • Fenspiride;
  • Bamelin;
  • Fexofenadine;
  • Ebastine;
  • Levocetirizine;
  • Desloratadine.

Treatment hives during pregnancy

Антигистаминные препараты при крапивнице: как правильно применять?During this period, all medications, even antihistamines, writes a doctor. Forbidden to take drugs illegally and without controls.

For pregnant characteristic rash allergic in nature, especially in the context of consumption of junk food (salty, spicy, sweet, citrus).

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In the first trimester to take antihistamines undesirable because there is a risk of pathological effects on the baby.

For example, Tavegil and Astemizole have embriotoksicescoe action, and Betadrin and Diphenhydramine can cause uterine contractions, resulting in possible spontaneous abortion.

In the 2nd and 3rd trimesters antihistamines can be drunk only in accordance with the recommendation of the allergist and only when the benefits outweigh the potential risks.

Often prescribed such drugs as Telfast, loratadine (claritin), Cetirizine. If there is an acute manifestation of urticaria, it is possible to accept Suprastin.

It should be noted that not all drugs help to get rid of symptoms. In this case, the specialist or prescribe you a different medication or prescribe hospitalization with the subsequent injection of antihistamine medicines.

The advantages and disadvantages of the use of antihistamines

Антигистаминные препараты при крапивнице: как правильно применять?In the treatment of urticaria is the first medication that will be prescribed to you by the doctor. Of course, every drug has its contraindications and side effects, but in General, they have similar benefits.

Almost all medicines are available at cost. Besides their use at home (with the exception of injection). After taking the effect is visible almost immediately (reduces irritation, itching, swelling).

From the disadvantages of possible to note a fairly extensive list of contraindications, side effects, and addictive, as a result, the drug becomes ineffective or does not help at all.


Treatment of urticaria with antihistamines is dependent on symptoms, the course and nature of the disease.

Most popular today are the medicine for 4 generations, causing fewer side effects than their predecessors.

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Despite this, the hives should be treated only in complex, completely eliminating contact with the allergen and taking the hypoallergenic diet.

With the right way of life the rash and itching will rarely bother you. If you notice the first symptoms of urticaria, you should not self-medicate, it is only the specialist will identify the causes of the disease and prescribe the correct and effective treatment. Be healthy!

Author: Anna Derbeneva (dermatologist)