Immunoglobulin Allergy: who is appointed and how to decipher?
Hello, dear readers! If you have any suspicion of the presence of allergies, then be sure to consult a specialist-an allergist. Why do you think?
The allergist will prescribe special tests, the results of which will be possible to make an accurate diagnosis and identify the allergen. One of them is the analysis of immunoglobulin for allergies.
What kind of research and how to decipher the results? To learn the answers, read this article carefully.
It will talk not only about the analysis of immunoglobulin E, treatment of hypersensitivity by using human immunoglobulin G. This is the second form of specific substances that are produced in our body.
What is immunoglobulin E?
This specific proteins, which are produced in the human body In lymphocytes. Structure of immunoglobulin E unusual: 2 light and 2 heavy amino acid chains.
Specific proteins are able to bind to cells that produce histamine to fat cells. Such a property plays a significant role in the development of allergic attack.
Simply put, proteins E serve as one of the reasons for the attack of hypersensitivity. It is often increased in atopic and hypersensitive reactions:
- other rashes on the basis of hypersensitivity;
- asthma bronchial.
In addition to allergies, the IgE response is accompanied by immunity to intestinal parasites. If the person is infected with parasites, the level of this substance in the body increases. Also, it increases are suffering from aspergillosis (fungal lung disease) and similar diseases.
Why ultrasensitive analysis of assigned proteins.
Often the attack allergies are confused with other diseases. All because its symptoms associated with many other ailments.
For example, urticaria is the deterioration that may begin regardless of hypersensitivity. To make an accurate diagnosis, you must carefully examine the condition of the body ill.
And it can be done only through detailed analysis of blood. The blood taken from the finger, Vienna (in most cases). This procedure will not take much time, and passes with minimal pain.
The level of immunoglobulin E is beginning to rise/fall primarily for allergies. Other diseases that are also accompanied by the phenomenon are not as common in our time. Therefore, protein E is considered the most significant indicator of the presence of allergies.
How is such a study?
In the course of analysis the patient takes the venous blood, and always on an empty stomach (it is better to donate blood in the morning). Before Allergology can’t drink affect the absorption of histamine drugs and other medications that affect the protein E.
Interpreting results: what is normal?
The normal level of the protein E changes with age. The newborn of these proteins in the blood at all. Adolescents, their number increases to the maximum limit.
Below you see the list of values of immunoglobulin in the norm for people of different ages:
- babies under a year from 0 to 20 IU per milliliter of blood (newborn protein can be detected only if the mother and the baby allergies, while protein will be passed on with mother’s milk);
- children 1-5 years — 10-50 IU;
- 6-14 years — 20-60 IU;
- among adolescents, 100-200 IU;
- adults — 20 to 100 IU.
What’s worse: the drop or increase?
In fact, abnormal is both. Elevated levels can indicate a variety of ailments: allergic attack; pulmonary fungal pathologies; pathologies of the immune system; cirrhosis of liver; mononucleosis.
Fall, in turn, says: immunodeficiency, hereditary deficiency of gamma globulins.
Allergy sufferers in the process of exacerbation of hypersensitivity have to lower the level of immunoglobulin E.
For this purpose antihistamine medicines, but, unfortunately, they are unable to provide instant recovery. That can normalize the level of the above proteins in the blood faster than antihistamines? You will be surprised, but can handle other human immunoglobulin — G.
The use of immunoglobulin G against hypersensitivity
Preparation on the basis of the foregoing substances produced from plasma of human blood. Immunoglobulin G blocks the synthesis of the same protein E, thereby produces almost instant antihistamine effect.
The main indication for the use of the drug are atopic symptoms of hypersensitivity. Contraindications it a bit:
- the age of one year old.
The pros and cons of the use of immunoglobulin G is obvious. Due to minor contraindications and high efficiency the product has become popular and in demand. Reviews about it mostly positive.
The above anti-Allergy medicine available in the form of a solution for intramuscular injection.
The dosage is selected based on the age of the allergies: from one year to five years — one ml every four days (five injections); from five years and older, and adults — two milliliters of the same pattern.
After six months of being re antiallergic course for prevention. If hypersensitive hay fever, it is recommended to repeat treatment every year for a couple of months before the threat of spring-summer season.
The only downside of the medication is high price. It varies from 2 to 3 thousand rubles per pack, which is enough for a full course. Many will say that it’s too expensive. But imagine how much easier as hypersensitive, treat immunoglobulin G.
That’s about it. I hope the article was informative and interesting. It you can share with friends on social networks, if desired. By subscribing to the updates, you won’t miss new articles that are published daily. All the best to you!
The author: Elena Smirnova (dermatologist)