Warts giant Buske Levenshtein: symptoms, treatment
Hello dear guest. Today we will try a clear and understandable way to tell what is the giant condyloma.
In this article, we will discuss with you the disease of viral origin, which is an obligate precancerous condition is called condyloma Buske Levenshtein. Similar formations are similar in appearance with a verrucous squamous cell carcinoma exophytic growth.
Another name of the disease carcinomatosa pointed.
But before you find out how to treat the disease, we recommend you to obligatory reading the book «the Treatment of warts folk methods», which describes the most effective folk methods against the disease.
What triggered the disease?
The formation of giant buske Levenshtein is purely viral nature. The main importance is given to the human papillomavirus type 16. Some authors insist on the role of other HPV types: 33,31,1,18, 11,6.
The main ways of transmission — sexual and direct contact.
There are precipitating factors that play a significant role in the manifestation of clinical appearances:
1. Suppression factors of humoral immunity;
2. Suppression factors of cellular immunity;
3. Increased trauma;
6. Sexually transmissible infections (anaplasmosis, lesions of the genital cytomegalovirus, chlamydia).
It occurs both in young and elderly. This is a very large tumor that is the result of a merger of several pathological elements.
Its typical localization is the head of the penis, all foreskin, a rare tumor goes to the trunk of the penis.
There are other areas of the body, where it may form: ANO-rectal region, the skin of the perianal area, the female reproductive organs, groin and mucosa of the oral cavity.
When there is malignancy of the tumor?
A significant role in the rebirth of tumors belongs to external factors: corrosive environment, lack of hygiene or neglect, frequent and prolonged irritation of the inner layer of the foreskin and the penis head. As with all types of HPV in the formation of clinical manifestations involved the suppression of immunity.
For example, a giant tumour was formed at the place of the lesions of lichen planus or in the presence of concomitant diseases — etiology of lichen sclerosus.
The beginning is characterized by the appearance of nodular elements, small, similar to warts, papillomas. The disease progresses quickly, so it is difficult to distinguish the individual elements, as they tend to merge into a single conglomerate of large dimensions.
The tumor is on a broad basis, which is clear of vegetation and dispersal between them clearly expressed grooves.
Around the main tumor can be noticed isolated solitary lesions. Vegetation gradually increase in size, begin to be covered by scales and materiaalse.
In the existing furrows of the effusion accumulates, it can become infected, causing an unpleasant odor. Often the tumour suppurate.
A distinctive feature of the tumor called buske is progressive growth, although a bit slow. The disease is prone to frequent relapses, for it is always difficult for the patient. Giant condylomas are a danger for those who took long-term immunosuppressive medications, for pregnant women, patients with severe disorders of the immune status.
In addition to the externally visible exophytic rapid growth of the tumor, it grows inside, that is, in the underlying tissues. As you know, the tumor growth leads to the destruction of the organ (foreskin), the formation of fistulas, ulcerations, and invasion in the cavernous body. From malignant neoplasms occurs most often squamous cell carcinoma on the place where appeared.
The symptoms depending on localization:
The diagnostic criteria of the disease
The final diagnosis set by the doctor-venereologist. He conducts a differential diagnosis with the following diseases:
Wide, which are a manifestation of secondary syphilis;
Skin cancer squamous cell type.
To confirm the correctness of a diagnosis is carried out polymerase chain reaction for detection of human papillomavirus.
During surgical treatment the patient take the material for histological examination, which will enable a final diagnosis. Not to miss the process of malignant transformation specialists take material for histological verification of several parts of a tumor.
A morphological examination revealed the typical changes that are characteristic of genital warts but with a higher degree of severity.
For example, strongly expressed in the stratum corneum of the epidermis (thick) and tend to grow into the underlying tissue.
A symptom of the transition process is the detection of malignant cells characteristic of cancer in situ.
The only radical method is surgical. It is completely excised, carried destruction through biopreparatov all wound surfaces. Of drugs prescribed interferon-a and Bleomycin. In the postoperative period shows the drugs interferon Viferon, Reaferon, and Likopid.
Therapy with interferon has a positive effect on the subsequent recurrence rate. Drugs used intratekalno and systematically. A favorable effect on the course of the disease, Panavir, it is used in the form of a gel and rectal suppositories.
The positive effect is achieved at a time when the use of liniment cycloferon with. It is applied directly to the growths that causes stimulation of local immunity and their gradual disappearance.
Treatment avoid therapy radiation as a high probability of conversion process in anaplastic.
Foremost among preventive measures is hygiene sexual life. You should avoid promiscuity, frequent change of partners. A carrier of such warts is contagious. Condoms are not a method of protection, as the virus can be transmitted even through saliva, if you have lesions in the oral cavity.
They are potentially dangerous entities, because at any moment can transform into cancer.
Among the leading drugs are based on interferon, antiviral, tonic, vitamin complexes.
Prevention with medication is a last resort, since drugs entail a number of side effects, for example, disbacterios expressed by the organism sensitization.
Author: Anna Derbeneva, dermatologist.