Clostilbegyt — usage instructions
Clostilbegyt (or clomiphene) is a drug that stimulates the process of ovulation. The main function of the drug is to aid the body in the formation of an egg: clostilbegyt stimulated an increase in levels of gonadotropins. The pills may trigger the production of prolactin, high amounts of which prevents ovulation, for this reason, specialists prescribe other drugs that reduce the level of hormones in the blood.
The drug clostilbegyt take from 5 to 10 day menstrual cycle. The dose for each woman is determined individually, depending on results of tests for hormone levels, so a visit to the doctor before using the product required. In the period of taking the pills, it is important to consult with a specialist and do an ultrasound. The first survey is conducted after 7 days after taking the medicine, then the procedure is done every third day. As a result, the follicles should reach a size of 25 mm.
If the drug had no effect, and within three cycles of ovulation by clostilbegyt did not happen, the woman should be re-examined. Perhaps a disease of the reproductive system is stopping the action of tablets.
Composition and pharmaceutical form tablets
The main component clostilbegyt clomiphene is in the form of acetate. One tablet contains 50 mg of the substance. In addition to clomiphene in the preparation includes:
- potato starch;
- magnesium stearate;
- stearic acid;
- lactose monohydrate.
Tablets have a round flat shape. Clostilbegyt can have gray, white or light yellow color. Pills do not have any odor. The drug occurs by the oral route.
Clostilbegyt available in dark vials, tightly closed with a lid made of polyethylene. One vial contains 10 tablets. Clostilbegyt in the package there are instructions for use of the medicine.
How does Clostilbegyt
Part klostilbegit, the substance is a nonsteroidal antiestrogen structure. The clomiphene is getting into the body, affects oestrogen receptors in ovaries and pituitary gland that causes ovulation.
At low-estrogen pills contribute to the active hormone. If estrogen levels higher than normal, klostilbegit has anti-estrogenic effect. A small dosage stimulates secretion of prolactin by the pituitary gland. In case of overdose the secretion of necessary hormones slows down. Period when ovulation, dose-dependent, which will take the woman.
The drug has progestogenic and androgenic action.
The indications for prescribing medication
The doctor prescribes the patient, clostilbegyt with such pathologies as:
- amenorrhea: disgonadotropic, secondary and post-contraceptive;
- dysfunctional metrorrhagia;
- syndrome Stein-Leventhal;
- the chronic form of galactorrhea;
- malnutrition reproductive system;
For all the above indications is characterized by the absence of ovulation in women.
Clostilbegyt, is appointed for men, if the there is an inadequate number of sperm. During therapy they need to regularly check the semen. Bodybuilders take clomiphene, as it is believed that the components included in the composition, and restore the body after taking steroids: in medicine there is no official confirmation of this fact.
The drug is forbidden to take in the following situations:
- pregnancy at any time;
- intolerance substances included in the composition of tablets (most often the cause of sickness is becoming lactose, so people with diabetes should not take clostilbegyt);
- diseases of the liver and kidneys;
- ovarian cysts;
- uterine bleeding;
- oncological diseases of genitals;
- disruption of the pituitary gland;
- endometriosis, which affects the mucous membrane of the uterus (adenomyosis);
- dysfunction of the adrenal glands;
- vision problems;
- thyroid disease;
The drug in the presence of one of the contraindications is dangerous to women’s health.
Side effects clostilbegyt
The drug can affect body systems that are not associated with the sexual organs:
- Nervous system: dizziness occurs, lethargy, depression, sleepy, or, on the contrary, develops insomnia.
- Digestive system: nausea, vomiting, problems with a chair.
- Genitourinary system: increase in volume of ovary, menorrhagia, dysmenorrhea, pain in the lower abdomen, increased frequency of urination.
Less often there is an Allergy to the medicine, which appears on the skin rash. It is noted that there may be an increase or decrease in weight, blood flow to the face, blurred vision and pain in the breast.
Taking clomiphene increases the chance of twins, but there is a risk of ectopic pregnancy.
Drink alcoholic beverages while taking the pill is prohibited, as this may enhance the effect of the active medication. In addition, alcohol negatively affects the mental state of the patient. Women planning to become pregnant, it is strictly forbidden to drink to ovulation was successful.
If adverse reactions to the drug should stop taking clomiphene or reduce the dose.
Excessive consumption of the drug, the patient can develop symptoms such as nausea, vomiting, blurred vision, flushed face, women increase the size of the ovaries. Methods of treatment of overdose clostilbegyt not been developed, therefore, therapy aimed at the elimination of symptoms.
How and in what quantities to take the drug
Method of application is determined individually depending on what the reason is receiving the drug.
If ovulation stimulation clostilbegyt drug should drink once a day, 50 mg before bed. Tablet should drink a glass of water. The reception lasts five days, however, your doctor may change the term therapy in its sole discretion. If the medicine has not had the desired effect (after a month), it is necessary to increase the dosage to 100 mg and to take the pills for 5 days. One menstrual cycle may not take more than 750 mg clomiphene.
If ovulation has occurred, but the woman failed to conceive, the reception needs to be repeated. The dosage remains the same.
Men take clomiphene twice a day on 50 mg. the Course lasts about 6 weeks. During treatment it is recommended to consult a doctor.
Counterparts, and compatibility with other drugs
When contraindications to the use of clomiphene, the doctor will prescribe the patient’s other medications, similar on properties with this drug. The analogues include:
Without medical advice to replace the drug to another.
Clostilbegyt, combined with medications containing the hormone gonadotropin. With other drugs clomiphene does not interact.
Special instructions for use
Before taking clostilbegyt advised to read the annotation to the drug.
During treatment should regularly check the liver, ovaries, undergo examination of the vagina. Checked the levels in the urine of the hormone gonadotropin. Treatment must be under the supervision of a doctor.
The woman should be careful to perform actions that require her attention and activity because of the reception clostilbegyt may develop pathology of the nervous system, decreases the visual acuity.
It is advisable to take a course of medication that contains progesterone, if treatment is directed on elimination of infertility.
Clostilbegyt, sold only by prescription. Self-treatment can harm the body. Giving to children is prohibited.
The drug should be stored at temperatures not above 25 degrees. The place must be dry. Shelf life clostilbegyt – 5 years.