Indomethacin candle instructions for use in gynecology

The most convenient and effective form of non-steroidal drugs which have anti-inflammatory action, are rectal suppositories. Suppositories this group are applied directly into the rectum, but in some cases, in gynaecology they are also used in the vagina.

Indomethacin candles – the instructions for use in gynecology States that the drug is mainly relieves pain and has anti-bacterial action. Moreover, the indications, the variety and effect for any disease is good. Therefore, rectal suppositories indomethacin is widespread in medicine.


Description candles of Indomethacin based on the fact that they are white and form of torpedoes. The composition contains the active ingredient – indomethacin 50 mg, and there are candles on 100 mg of active substance. Thus, vaginal suppositories are the dosage is 50 mg, rectally – 100. Suppository has antiplatelet property, or, in other words, it inhibits the platelets from sticking together, and the inflammatory process in the form of light. The mechanism of action of indomethacin 50 mg based on the fact that they are not allowed to produce a substance that causes pain. Thanks to a convenient form, candles are rapidly absorbed and act immediately.


The preparation has the following indications:

  • inflammatory diseases that occur in the joints or surrounding tissues, for example, osteoarthritis, arthritis, tendonitis, capsulitis, tenosynovitis;
  • menstrual pain;
  • hemorrhoids;
  • muscle aches, pain after surgery;
  • prostatitis;
  • deformity of the spine;
  • gout.

Due to the fact that the drug reduces the pain in these diseases, it helps to improve the quality of life of all patients. While candles with indomethacin during pregnancy is prescribed when there is a probability of threat of miscarriage, and during childbirth as an analgesic.

Often doctors prescribe candles of Indomethacin for the treatment of hemorrhoids. According to the men this drug is much better and faster helps to cope with the discomfort and unpleasant sensations in this pathology. In the rectum the suppository dissolves, and through the venous plexus of the active substance passes directly into the blood, reducing spasms and swelling. Candles help to dissolve blood clots and prevent their reappearance. Similarly, the drug helps in prostatitis, where locates the pain in the abdomen.

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Indomethacin candles – the instructions for use in gynecology, provides for a maximum number of applications of the drug. Indomethacin 50 mg, you can apply up to three times a day, it all depends on the indications for use, and candles, 100 mg once a day.


Before applying you need to carefully wash hands with water and then have to get the candle out of the blister. Where to insert rectal suppositories known to all, but it should be done after enema to enhance the effect. The suppository is inserted directly into the rectum pointed end and it is desirable to introduce deep. The same should be done with vaginal of indometacin candles. Just to start, a woman must undergo hygiene procedures. Insert a candle is better on the night, in the supine position, but in some cases when using candles twice a day after use lie down. Treatment usually lasts 14 days, but sometimes less. It all depends on the disease and condition of the patient.

Use in gynecology

Of indometacin candles are used in medicine in many diseases. Among them it is possible to identify the main gynecological problems:

  • severe pain during menstruation;
  • cystitis;
  • ovarian cyst;
  • adnexitis;
  • inflammation of the genital organs;
  • the pain in endometriosis;
  • fibromyomata of the uterus;
  • as a preventive measure, did not appear adhesions after surgery.

Use in pregnancy

Candles with indomethacin in gynecology is used in the first and second trimester when risk of miscarriage. In addition, they are used with increased uterine tone. This pathology can lead to the fact that the fetus may develop hypoxia, detachment can exfoliate and pregnancy be interrupted. Indomethacin, a part of the drug, quickly stopping the production of hormones that contribute to toning the muscle tissue of the uterus. But it is worth noting that in some cases the spark can cause abnormalities in the fetus. Through research it was found that the active ingredient crosses the placenta and may harm the baby, so the drug should not be used by the end of the second trimester.

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During lactation Indomethacin candles cannot be used because the active substance passes into breast milk and stands out with him.

Side effects

The active ingredient included in the composition, may cause side effects of any woman. Patients often feel nauseous after using candles. It’s not as dangerous as abdominal pain, diarrhea, and even bleeding. Sometimes there is a hepatitis and jaundice, but these side effects were rarely detected.

The drug also affects the nervous system of the patient, so the person feels dizziness, headaches, happen fainting, insomnia and mental disorders.

Other side effects:

  • blood can change the number of cells, therefore there is epistaxis;
  • allergic reactions: skin rash, asthma, swelling of the throat;
  • severe fatigue and drowsiness, headache, nervousness, depression, anxiety;
  • eye pain, double vision;
  • ringing in the ears;
  • loss of appetite, diarrhea, constipation, flatulence, exacerbation of ulcerative colitis;
  • jaundice or inflammation of the liver;
  • renal failure, increased protein and urea in the urine;
  • tachycardia, hypertension, pain in the heart region;
  • in the blood may increase the concentration of glucose and potassium, when you enter suppository burning sensation can also occur.

If side effects appeared on the first day of application of the suppository, it’s a reason to visit a doctor who will help to adjust the chosen treatment regimen.


According to the above mentioned side effects, and a lot of them, you should list the main contraindications of the drug:

  1. Children up to age 14 years.
  2. Allergy to components of drug.
  3. Hypersensitivity to the active substance.
  4. Disorders of the blood.
  5. Violations of functions of kidneys and liver.
  6. The third trimester of pregnancy.
  7. Peptic ulcer disease.
  8. Disease of the optic nerve.

Remember, the spark of indometacin incompatible with alcohol, so during a treatment it is best to abandon the use of alcoholic beverages, because they increase the side effects of the drug.


At this moment in pharmacies there are analogues of indometacin suppositories. Their cost varies and depends on the number of suppositories in the packaging and milligrams. Sometimes doctors even suggest alternate medication with its counterparts, to avoid any habituation of the patient and reduce the risk of side effects. In such cases, the therapeutic effects are not reduced. The analogues of the drug are:

  • Ketoprofen;
  • Naproxen;
  • Movimed;
  • Diclofenac;
  • Indoline;
  • Indomethacin.
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All of these analogs have the same effect as Indomethacin, only have other indications and side effects therefore, before applying need to read the instructions. Counterparts may be cheaper but before buying you should make sure that the product contains the required amount of active substance. The price of the medication depends on the manufacturer, for example, the preparation of foreign representative would be more expensive than local.

Interaction with other medications

With caution the drug should be used with such drugs as:

  • aspirin;
  • paracetamol;
  • cefoperazone: can blood clots appear;
  • drugs, which include ethanol, corticosteroids, and colchicine diflunisal: the risk of complications of gastrointestinal diseases and bleeding;
  • antihypertensives and diuretics: a reduction in their effectiveness.


When you consider all the reviews about the drug, it can be concluded that Indomethacin by suppository is effective. Moreover, the range of his actions big indications also exceed all expectations, but a lot of contraindications. Before applying it is important to consider all the contraindications, to prevent undesirable side reactions. Sometimes the adverse reaction can cause serious problems than the disease itself. Before use, be sure to consult with a healthcare specialist.