Is it possible Viferon vaginally when menstruation
Immunomodulatory suppositories Viferon can be used not only rectal but also vaginal method. The main indications in this case are different urogenital infectious and inflammatory, herpetic and fungal pathology. With the introduction into the vagina the drug effectively and safely improves local immunity, normalizes microflora and preventing the recurrence of diseases.
Increasingly, in the complex therapy of different diseases are being used drugs, improves overall and local immunity. One of the most popular, safe and effective Immunostimulants are candles Viferon on the basis of artificially synthesized human interferon.
Despite the fact that the suppositories are intended primarily for rectal administration, the drug has found wide application in gynecological practice for the successful treatment and prevention of urogenital and some fungal infections.
Description and effect of the drug
Viferon is a complex drug, which has antiviral, antibacterial and immunomodulatory effects. Its main component is a recombinant interferon alpha-2b – special protein produced by human cells in response to the introduction of viruses. The formulation also includes ascorbic acid and alpha-tocopherol acetate, which are the stabilizers of the cells and antioxidants, significantly increases the activity of interferon.
As the basis of suppositories used cocoa butter with a small inclusion of confectionery fat, facilitate easy introduction and rapid absorption of the main active ingredient mucous membrane of the rectum or vagina. While rectal components of the drug goes directly into the blood, accelerating the process of development of its own interferon and immunoglobulins, thereby enhancing General immunity.
With the introduction of the vagina with interferon has a beneficial effect on local flora and enhances the protective properties of the mucosa against the effects of viruses, bacteria and fungi.
Viferon candles are in the shape of a bullet with a diameter of 1 cm with a small hole on the end for ease of insertion. The hue varies from white to light yellow patches or marble designs. The tool is produced with different concentrations of the main active ingredient: 150000, 500000, 1000000 or 3000000 IU. The dose is prescribed by the physician depending on the age of the patient, nature of disease and presence of comorbidities.
The shelf life of the immunomodulator is 24 months. Due to the low-melting suppository bases should be stored at temperatures between +2 °C to 8 °C. Dispensed without a doctor’s prescription.
Indications for vaginal use
In gynecology suppositories have proven themselves in the complex treatment of the following diseases:
- genital infections (trichomoniasis, chlamydia, ureaplasmosis, gardnerellosis, cytomegalovirus infection, bacterial vaginosis);
- other infectious-inflammatory urogenital diseases;
- papilloma infection (HPV);
- fungal infections (mycoplasmosis, recurrent vaginal yeast infection );
- herpes infection genital type.
During pregnancy in the prevention of pathologies that arise due to the weakening of local immunity, also often prescribed candles Viferon vaginally. Some experts resort to this medication for some complications of pregnancy or the risk of intrauterine infection.
The expediency of application of the drug not only due to its beneficial influence on the condition of the female reproductive system, but also an effective protection of the fetus, to which many diseases of the mother can be devastating.
Regimen and dosage of the drug in rectal and vaginal use, as a rule, do not differ. Often adult patients prescribed one suppository 500 thousand IU twice a day. Depending on the nature and severity of the disease, the dosage may be increased.
For the most effective action of interferon is necessary to enter the candle deeply into the vagina always at the same time, with an interval of 12 hours. Do not want to use melted candles and fresh suppositories should be replaced by a new one. After the introduction, it is recommended to lie down for 15 – 20 minutes to speed up the onset of action of the drug and prevent it from slipping.
The duration of intake of the drug is 5 – 10 days. For most urogenital abnormalities without complications just one or two courses of therapy. In the treatment of recurrent candidiasis, herpes infection, and the presence of diseases associated with decrease in the General immunity, the number of courses the introduction of the spark increases to three-four or more with an interval of 5 days, depending on the doctor’s recommendation.
In identifying the patient with HPV, which is currently not developed effective methods of treatment, with the aim of immunomodulation candles Viferon may be administered every 4 to 6 months.
Treatment and prophylaxis of infections and inflammatory pathologies of the genital tract in pregnant women is slightly different. They also prescribe suppositories dosage of 500,000 IU twice a day, but the introduction of the drug is as follows:
- Since the gestational period of 14 weeks, daily for 10 days.
- In the last 9 days 3 times with an interval of 3 days.
- Every four weeks for 5 days before delivery.
To increase the efficiency of immunomodulator allowed the alternation of rectal and vaginal administration of suppositories. When clinically indicated duration and regimen can be changed at the discretion of the physician.
Use during menstruation
Many patients are concerned with the question whether it is possible to use candles at the monthly. The effectiveness of prevention and treatment of most diseases is not dependent on the menstrual cycle of a woman.
However, when aggravation of of genital herpes or localization of foci of infection in the vulva and lower third of the vagina it is recommended to replace sanitary pads tampons to avoid contact of the lesions with bleeding. If it is for some reason impossible during menstruation should be administered suppositories in the rectum.
The main contraindication is the first trimester of pregnancy and hypersensitivity to the individual components of the drug (most often the allergen is cocoa butter).
Side effects and overdose
As for rectal and vaginal use side effects are quite rare. Some patients complain of General weakness, muscle and headaches, nausea, and allergic reactions to components of the candle (itching, discomfort, flaking, rashes in the genital area).
As a rule, these complications disappear a few days after discontinuation of the drug. In case of these symptoms or increase after discontinuation of therapy, you must inform the attending physician.
Yellowish orange discharge in the vaginal process of the use of candles are not a side effect and a reason for the withdrawal of the drug.
Cases of overdose have not been identified.
The reviews about the drug
Regardless of the method of application regarding this drug among doctors and patients is ambiguous opinion. The mechanism of action of recombinant interferon Alfa-2b on the immune system are not fully understood, and any obvious signs of its effectiveness are often lacking, in contrast to the traditional means of treating infections.
However, most women who regularly use candles Viferon for vaginal administration, note the following:
- to reduce the frequency of recurrence of diseases;
- rapid onset of improvement when co-administered with anti-inflammatory or antibacterial drugs;
- no violations of the vaginal flora during pregnancy;
- safe use, does not cause side effects.
It is worth noting that, despite the safety of the drug Viferon candles are a drug which should be administered under the supervision of a physician. To self-medicate and change doses of medication and the duration of therapy is strictly prohibited.