Nose drops Oxymetazoline: application instructions and analogues

How to take nasal drops Oxymetazoline?

Oxymetazoline is a drug that belongs to the group of agonists. The tool contributes to the narrowing of blood vessels which are dilated due to inflammatory process in the nasopharynx.

After instillation of the solution u of the patient reduces the swelling of the mucous membrane of the nose and restores breathing. Signs of improvement can be seen already after 15 minutes after use of the drug. The therapeutic effect lasts for 10-12 hours.

Release form

Oxymetazoline sold over the counter in the form of drops or spray. The volume of the bottle is 10 or 20 ml.

The drug

In the present solution of Oxymetazoline hydrochloride, which helps constrict blood vessels of the mucous membranes of the nose. Depending on the product form the content of active substance is 0.1 mg, 0.25 mg or 0.5 mg. When selecting the tools the doctors take into account the patient’s age and individual characteristics.

Pharmacological action

The drug is in contact with the mucous membrane of the nose helps to reduce swelling. In humans eliminates congestion and reduces the production of mucus.

During the course of treatment do not exceed the dose specified in the instructions. The solution has a local effect and is excreted from the body in a natural way.


Oxymetazoline should not take patients suffering from diabetes or gipertrihoza. Doctors do not recommend the use of nasal drops with Oxymetazoline hydrochloride for patients with atrophic rhinitis.

Oxymetazoline contributes to high blood pressure. Solution may cause damage in atherosclerosis and hyperthyroidism.

The drug is contraindicated to people who have the identified Allergy to components of Oxymetazoline.

Side effects

After instillation of the solution the patient may experience unpleasant symptoms:

  • a strong burning and itching in the nose;
  • a sharp jump of arterial pressure;
  • dryness of the mucous membranes of the nasopharynx;
  • abnormal heart rhythm;
  • insomnia due to anxiety.

Specialists severely restricted term use of Oxymetazoline. This is due to the fact that prolonged use of the drug may lead to congestion of the mucous membranes.

Prolonged use leads to dystrophic changes of mucous membranes of the nose. To avoid complications the doctor will prescribe solutions reduced the content of active substances.

It is forbidden to take simultaneously with Oxymetazoline

Reduces the medicinal effect of anesthetics because it slows their absorption.

The solution is not to bury the nose if the patient is taking agents that increase pressure. This can lead to serious consequences in glaucoma.

Oxymetazoline is incompatible with antidepressants, as this can lead to hypertension and arrhythmias. The drug can be instilled only 2 weeks after their cancellation.

Oxymetazoline causes the development of mucosal atrophy. Before using the drug should consult a doctor.

Part of the solution benzalkonium chloride some patients it causes irritation and swelling of the mucous membranes of the nose.


Instillation of solution into the nose more than 5 days leads to the fact that the patient is disturbed, the process of regulation of fluid in the cells of the mucous membranes. Prolonged use of the drug causes the patient addictive.

This reduces the therapeutic effect of Oxymetazoline. To restore nasal breathing the patient had to resort to the drops more often.

The excess of the dose prescribed in the instructions can be recognized by several signs:

  • patient’s pupils dilate;
  • appear nausea;
  • swollen lungs;
  • the body temperature is lowered and inhibited nervous system.

Overdose is especially dangerous for young children. The kids have a quite rapidly atrophy of the mucous membranes.

How to take drops

Instructions for use of nose drops Oxymetazoline requires strict adherence to dosage. To help adult patients, it is sufficient to enter in the sinuses 1-2 drops of a solution containing 0.05% of active substance. To eliminate symptoms of rhinitis remedy should be instilled 2-3 times a day.

In the treatment of children aged 1 to 6 years is recommended to use a preparation with a reduced concentration of Oxymetazoline hydrochloride. The solution should be instilled 1-2 drops 2-3 times a day.

Treatment of babies under one year requires a special approach. Doctors prescribe to young children a drop containing 0.01% active ingredient.

Due to such a low dose to avoid side effects that often occur in your baby. Need to drip 2-3 times a day, 1-2 drops.

Important! Oxymetazoline cannot be used more than 5 days. In the absence of positive results, you need to contact the doctor.

For the treatment of children under 6 years are allowed to use the drug only in the form of drops. This prohibition stems from the fact that the spray in this age might cause suffocation. Each bottle is equipped with a special attachment that facilitates the process of injection tools. The drug should be injected into each nostril 2-3 times a day.

Can I take nasal drops during pregnancy?

Oxymetazoline is considered a strong drug that acts about 10 hours.

It can have a negative impact on the development of a fetus.

Especially dangerous are these drops for 1 and 2 trimester when important organs are formed the baby.

Doctors do not recommend the use of Oxymetazoline for the treatment of rhinitis during this period.

How can I replace Oxymetazoline?

There are analogues which can be used as an alternative to the Oxymetazoline.

Such drugs include:

  • Afrin;
  • Nazivin;
  • Nazol;
  • Nanospray;
  • Fervex;
  • Netopen;
  • Noksprey.

Doctors prescribe these funds in cases when the patient there is an individual intolerance to the components of the Oxymetazoline.


Oxymetazoline is designed to narrow vessels and reduce swelling of the mucous membranes. The drug takes effect immediately after it reaches the surface of the mucous membranes of the nose. After a few minutes the patient gets rid of nasal congestion, complicating breathing.

The duration of the solution reaches 10 hours. However, such a remedy does not correct the cause of the common cold, but only temporarily relieves symptoms of the disease. Patient do not use Oxymetazoline more than 5 days, as it has a negative effect on the mucous membrane of the nose.

READ  A deviated septum: treatment, consequences, and causes