Combines Duo eye drops: manual, price, reviews, analogs

Комбинил Дуо глазные капли: инструкция, цена, отзывы, аналогиCombines Duo is a combined ophthalmic drug that has anti-inflammatory and antibacterial action. Assigned topically as eye drops. The main indications for its use are:

  • conjunctivitis;
  • keratitis;
  • dacryocystitis;
  • uveitis;
  • blepharitis and others.

In addition, it is used for prophylaxis after various injuries of the eye and in the postoperative period.

The drug exerts its therapeutic effect at the expense of Ciprofloxacin and Dexamethasone that are part of it. Generation fluoroquinolone antibiotic is effective against many microorganisms, both gram-positive and gram-negative. Dexamethasone as a representative of corticosteroids has a pronounced anti-inflammatory effects, and actively suppresses allergic reaction.

The drug has good penetration into all ophthalmic structures. This greatly increases its efficiency. Maximum action, he reaches a half-hour after instillation. In front of the camera the content of active substances is the largest.

The composition and form of issue

The active components of the drug Combines Duo are:

  • ciprofloxacin – an antibiotic of the fluoroquinolone group;
  • dexamethasone – a corticosteroid with anti-inflammatory activity.

The release form is eye drops. One vial contains 5 ml. It is made of plastic, so it is convenient to carry and use anytime when needed.

Method of application

Комбинил Дуо глазные капли: инструкция, цена, отзывы, аналогиMethod of application of the drug Combines Duo looks like the following:

  • buried one or two drops;
  • the rate of burrowing during the day is four to six times a day, that is the interval between the instillation should be between 4 to 6 hours;
  • the duration of treatment is determined individually depending on the degree of the pathological process severity and tolerability of the drug, but it should not exceed 2-4 weeks due to development of adverse effects.
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The main contraindications when not to use this drug are:

  • hypersensitivity to the drug;
  • children and adolescents under the age of 12 years;
  • gestational period;
  • breast-feeding;
  • viral disease;
  • mycoses of the eye.

Side effects

Комбинил Дуо глазные капли: инструкция, цена, отзывы, аналогиOverall, the drug has a good tolerability. However, in some cases may encounter some side effects.

These include:

  • redness of the eyes;
  • itching and burning;
  • swelling;
  • blurred vision;
  • a secondary bacterial infection and some other complications.

Special instructions

Special instructions to be followed in the treatment of ophthalmic drug Combines Duo, are as follows:

  • In the case of simultaneous combination with other ophthalmic drugs, you need to make a 20-minute break to drop did not mix.
  • On the background of treatment with this drug may decrease the ability to drive a car due to blurred vision.
  • Unopened vial must be stored not more than 2 years, and in the open – not more than one month.
  • Storage temperature – cool (optimally from 8 to 15 degrees), the place of storage should be darkened.
  • Dropper of the bottle should not touch structures of the eye, as this may cause infection content.
  • You should also avoid touching foreign objects.
  • The course of treatment with this drug should not exceed that recommended by the ophthalmologist, as this may lead to negative consequences, primarily, to the increase in intraocular pressure, this background may develop atrophy of the optic nerve, damage to the retina, which is accompanied by a decrease or loss of vision, moreover, against the background of the prolonged use decreases local immunity, which creates conditions for the development of secondary infection of bacterial origin.
  • In case of purulent inflammatory diseases of the eye: the drug is administered with caution.
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    Elena, 33 years

    «Helps to get rid of inflammatory diseases of the eye. The drug is extremely effective. Every morning, I could not open the sticky pus from the eyes, I had conjunctivitis. In the clinic I was prescribed Combiner Duo. The next day I felt better. Thanks drops quickly recovered, the drug works on hurrah».

    Anastasia, age 38

    «Drops effective treatment. You need to use them within a month after opening the bottle. Was treated repeatedly conjunctivitis, but after 2 weeks of using, the drops begin to thicken, to apply them it becomes scary. The medication starts to sting the eyes.»


    Комбинил Дуо глазные капли: инструкция, цена, отзывы, аналогиThe analogues used in case of intolerance Combine Duo. Analog drugs have similar but not identical mechanism of action. In addition, the composition of their represents Kombinera Duo components. In most cases, you have to replace to appoint two drugs and antibacterial and anti-inflammatory.

    The main drugs with antimicrobial activity that can be substituted Combiner Duo are:

    • Chloramphenicol;
    • Sulfatsil sodium;
    • Sulfacetamide;
    • Floksal;
    • Cipromed;
    • Tobrex;
    • Normaks;
    • Oftaquix, and many others.


    Price eye care drug Combines Duo is from 200 to 300 rubles depending on the pharmacy network, which is engaged in its implementation. In General it is quite acceptable, given that the drug is a combo – contains an antibiotic and a corticosteroid.