Signitzer eye drops: manual, price, reviews, analogs

Сигницеф глазные капли: инструкция, цена, отзывы, аналогиSignitzer is an ophthalmic drug for topical application of fluoroquinolone. It is used for the treatment of infectious processes of the eye such as:

  • conjunctivitis;
  • blepharitis;
  • keratitis;
  • uveitis;
  • iridocyclitis;
  • dacryocystitis, etc.

Also it can be used prophylactically before and after eye surgery to avoid the development of infectious complications. The drug is effective against the following microorganisms:

  • romanella;
  • gonococcus;
  • hemophilic Bacillus;
  • Pseudomonas aeruginosa;
  • Streptococcus;
  • staph;
  • chlamydia;
  • anaerobes and others.

The composition and form of issue

The main active ingredient is Levofloxacin Signicate. This antibiotic of the fluoroquinolone group of the last generation. It shows increased activity against intracellular bacteria, which escape from under the therapeutic effects of other antibacterial drugs.

The composition Signicade includes excipients that act as stabilizers and preservatives. They allow the drug to persist for a long time. However, they may be associated side effects.

Method of application

Сигницеф глазные капли: инструкция, цена, отзывы, аналогиMethod of application of the drug as follows:

  • a single dose should be two drops instilled in each eye;
  • frequency of instillation in the first days is 8 times, that is every 2 hours, the next day it can be reduced, as the drug accumulates in the tissues, exerting its therapeutic effect;
  • the duration of treatment should be as short as possible (optimally, if it is equal to 5 days), so without a consultation with the ophthalmologist in this situation can not do.


List of contraindications to the use of Signicate not great. They are practically the same for many antibacterial drugs. To these situations, when the use of this drug is unacceptable, include:

  • one year old babies;
  • gestational period;
  • lactation period;
  • individual intolerance of the drug.
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Side effects

Сигницеф глазные капли: инструкция, цена, отзывы, аналогиSide effects when using Signicate not often recorded. However, when they occur, immediately consult a doctor to decide whether further treatment.

Side effects include:

  • itching;
  • burning;
  • redness;
  • swelling of the eye;
  • increased tears;
  • fear of light, etc.

Special instructions

Special instructions to be followed in the treatment process according to ophthalmological drug are as follows:

  • Do not use this drug while wearing contact lenses, as it can cause clouding due to benzalkonium chloride.
  • The interval between instillation of other ophthalmic drugs should be 15-20 minutes, so that they do not engage each other in interaction.
  • In the process of backfilling should try to avoid touching the dispenser of foreign objects and structures of the eye, so as not to infect the contents of the vial.
  • It should not be long time to use this medicine as it may lead to activation of the fungal flora and development of antibiotic resistance.
  • Face down the drug be stored up to 3 years.
  • Reviews

    Alina, 26 years

    «These drops was prescribed to my son when we was two, he went into the garden and picked up a viral conjunctivitis. Initially it was treated with tetracycline ointment, which advised the doctor. Got worse eyes festering awful and almost didn’t watch was terrible. And after Signicate (prescribed ophthalmologist in private office) improvement occurred after a couple of hours. Dripping a week twice a day, even washed the tea, and it went unnoticed. So all I recommend! Only downside: we found a drop only in the third pharmacy in a row, all the others offered to order and wait a day.»

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    Eugene, 23 years

    «With this medication I had to meet you after the birth of a daughter. I wear lenses that need to be removed at night. But because of chronic fatigue, night feedings often began to forget to do it. And earned a keratitis, a very unpleasant thing. Tried to be treated independently, until it got to the point that eyes are swollen, terribly watery and literally covered with small ulcers. The doctor at the clinic came as a shock and was discharged, Signalf. Relief came immediately. That confused – the instructions do not use during lactation, and I’m still feeding at night, breast-my daughter. But perhaps the situation was critical, the drops really saved me.»


    Some analogues are used in the case when the patient for some reason can not use this drug, which he was appointed ophthalmologist. It may be intolerance to the drug, the lack of it at the drugstore, the high cost etc. Drugs substitutes are similar, but not identical mechanism of action. In their composition usually contains a different antibiotic, and you need to consider when changing. Not all organisms are equally sensitive to different antibiotics.

    Сигницеф глазные капли: инструкция, цена, отзывы, аналогиCounterparts, which can be recommended in this case include:

    • Chloramphenicol;
    • Sulfacetamide;
    • Cipromed;
    • Floksal;
    • Tobrex;
    • Oftaquix;
    • Normaks and some others.


    Price eye care drug Signitzer ranges from 200 to 300 rubles, depending on the pharmacy network, which is engaged in its implementation. Overall it is a great combination of price and quality, so patients show high treatment adherence with Signicate.