Xalacom eye drops: manual, price, reviews, analogs
Xalacom is protivoglaucomny tool for lowering pressure inside the eye.
Thanks to the combination of the main components of the drug (timolol and latanoprost), which have a different mechanism of action, provides a more effective reduction of pressure inside the eye, in contrast to that, as if each of these composite components were used separately.
Timolol is a nonselective β-blocker that does not impact negatively on the heart muscle. The impact of this substance on reduction of pressure occurs as a result of a decrease in the formation of aqueous humor. Under the action of timolol there is a slight improvement of the outflow of this moisture. Timolol is absorbed into the systemic circulation.
Latanoprost, an analog of prostaglandin, the pressure inside the eye decreases due to the fact that helps to improve outflow of aqueous humor. And to generate this component is not affected. It is absorbed through the cornea of the organ of vision, reaching a maximum of watery moisture after 2 hours after treatment instillation. Latanoprost and also in some quantities into the systemic circulation.
Xalacom begins to exert a therapeutic effect after use within an hour. The maximum value achieves the effect for 6-8 hours. When the drug is used repeatedly, the pressure reduction is maintained after the introduction during the day. Since its components can enter the bloodstream, you may experience various side effects which require discontinuation of application Xalacom.
The composition and form of issue
Available in the form of drops for eye, solution which is colorless and comes in a bottle with a volume of 5 ml Main active substances are latanoprost and timolol, and the auxiliary – sodium dihydrogen phosphate, sodium hydrogen phosphate anhydrous, sodium chloride, benzalkonium chloride, water.
Indications for use
Is assigned in order to reduce the high pressure inside the eye when:
- elevated IOP;
- open-angle glaucoma.
Still Xalacom used when other protivoglaucomny tools do not provide the necessary therapeutic effect.
Method of application
The drops are applied topically for adults and older people buried on the 1st once per day at 1st drop. Even if one treatment instillation was skipped, then the treatment continues in the usual manner. If Xalacom used in conjunction with other eye drops in treatment of the disease, between instillation of funds necessary to comply with a 5 minute break.
You cannot use these drops:
- people with hypersensitivity to any component means;
- in pulmonary diseases of a chronic nature;
- if you suspect or diagnosed with asthma;
- if sinus bradycardia;
- in heart failure;
- in cardiogenic shock;
- during pregnancy and breastfeeding.
Important! Medication against glaucoma must appoint the attending physician to determine the dosage and duration of treatment.
When using Xalacom may develop various side effects linked to the presence of substances such as latanoprost and timolol. Side effects can be local and system-wide. Among the local can be identified:
- the emergence of foreign body sensation;
- the pain in the eyes;
- the reduction sensitivity of the cornea;
- drooping eyelids;
- darkening of the eyelid skin;
- change the color of the iris (the most common for people with such colors iris: yellow-, blue-, green-brown);
- change eyelashes;
- swelling of the macula.
- the appearance of pain in the head;
- shortness of breath;
- noise in the ears;
- the appearance of a skin rash;
- increase in blood pressure;
- dry mouth;
- a heart rhythm disorder;
- pain in the thoracic spine;
- disturbances in the Central nervous system;
- the appearance of syndrome of lupus.
Possible side effects and other ingredients are preservatives. But in any case, if you experience any unpleasant and painful sensations in the body and throughout the body, you should stop using the drops and consult an ophthalmologist.
If you use drops at the recommended dose to happen of overdose can not. And there is no information on overdose Xalacom. However, if you overdose on latanoprost possible conjunctival redness and irritation of the organ of vision. In case of overdose with timolol may experience bronchospasm, bradycardia, decrease AD, and even be cardiac arrest. If you experience such signs of overdose, symptomatic and supportive therapy.
After accidentally ingest Xalacom in large doses, you may experience abdominal pain, dizziness, vomiting, increase sweating and to develop fatigue. However, these features are not very pronounced and go away on their own after 4 hours, not requiring treatment.
Interaction with other drugs
Any research on how this tool interacts with other drugs, was carried out. But it is not necessary to apply together with timolol antiarrhythmic drugs, calcium channel blockers, cholinomimetics, cardiac glycosides, MAO inhibitors, painkillers as possible, which will slow down the heart rate and decrease AD.
Cannot be used in conjunction 2 β-blocker or prostaglandin 2. Diabetes is better not to use β-blockers, probably because the manifestation of acute hypoglycemia.
Sometimes timolol together with adrenaline can affect the pupil, leading to its expansion, while these drops do not affect the pupil to change size.
People who have a severe reaction to allergens, when using β-blockers may again be reaction to these allergens. Treatment β-blockers can lead to what might be hiding the symptoms of hyperthyroidism, and with the cancellation of this drug, the patient’s condition can rapidly deteriorate.
The drug is released only by prescription. Before you appoint Xalacom, the ophthalmologist should inform the patient that a possible change in iris color as a result of its use. This process usually is irreversible.
These drops patients with mixed color of the iris, are appointed only when other medications do not cope with the task of reducing the pressure inside the eye or are poorly tolerated by patients. If the iris pigmentation occurs quickly, the doctor may stop the therapy. Especially noticeable that the iris color changes when the treatment to be only one eye.
Caution need to use these drops for people who have damaged posterior capsule of the lens a aphakia, pseudophakia or there is a high risk of macular edema.
Before the procedure, instillation of a solution you need to remove the lenses and put them back 15 minutes later. This is due to the fact that the benzalkonium chloride present in the composition of the droplets can cause damage to the lens, bringing them in unsuitable condition.
You can’t use drops during pregnancy and breastfeeding. But if they are appointed during lactation, breastfeeding should not stop the period of treatment of diseases of the eye.
Should be careful to use this drug when angle-closure glaucoma in the acute attack and in congenital glaucoma, because there is no information about how it can affect the human body in these diseases.
After the solution was Saipan in the eye, you may experience blurred vision, which lasts a few minutes. Therefore, immediately after use Xalacom not to drive or work in areas that require increased attention. You need to wait some time until vision is restored to normal.
To use drops need no more than 1 time per day, because more frequent use can lead to the fact that the effect of reducing the pressure inside the eye will be weakened. When used together, these drops and other means of instillation must be carried out interval, which should be not less than 5 minutes.
Bottle with drops that has been opened, use within one month. Keep the preparation you need in a place where it is dark and where it will not be able to get children.
Positive. Among buyers drops Xalacom mostly have positive reviews. They are well reduce pressure inside the eye in glaucoma. They are easy to apply and you only need to dig once a day.
Negative. The disadvantages of the drug include high cost, small bottle. For some people, it caused side effects eyes were red and swollen eyelids.
Similar to this tool are:
- Drops fotil;
To assign the same drug, in the same way as Xalacom, can only be attending physician. Self replacing one means the other is not recommended.
The cost of these drops in Russian pharmacies varies from 660 to 750 rubles.