Don — a cure osteoarthritis: pharmacological action of the drug

Дона - лекарство от артроза: фармакологическое действие препарата

An effective remedy against osteoarthritis

«Dona» is a modern medicine, chondroprotector. It is used for the treatment of joint diseases that cause damage to the cartilage. Among these pathologies, it is possible to allocate deforming osteoarthritis of various joints.

Chondroprotectors not only eliminate the symptoms but also have a positive impact on the cause of the disease. They restore the cartilage of diseased joints, and normalize the formation of synovial fluid and its lubricating characteristics. This combined action is particularly effective for the treatment of early stage osteoarthritis.

Pharmacological and therapeutic action of the drug

Medicine produces the Italian pharmacological company «Rottafarm». The active ingredient of the drug is glucosamine sulfate, which is one of the main chondroprotection existing in medicine at the moment. Dona has a positive effect on metabolic processes, improves the metabolism of cartilage and bone.

Contained in medication glucosamine sulfate has a positive effect on the cartilage tissue of the patient’s joint, prevents the deformation of the cartilage, contributes to its recovery. The drug speeds up the synthesis of cartilage tissues, which are based on cartilage cells — chondrocytes.

The drug is «don» has anti-inflammatory properties, reduces pain in the joints, restores their function, prevents the development of osteoarthrosis.

Дона - лекарство от артроза: фармакологическое действие препарата

Part medications include beneficial effects on joint health vitamins and minerals

Don stimulator repair cartilage that has anabolic, anti-inflammatory, chondroprotective, anti-catabolic action. The glucosamine is an aminosaccharide with a low molecular weight, it is a natural component of the cartilage joint tissue. It activates the formation of synovial fluid tissue cells of the cartilage destroying enzymes, causing destruction of cartilage, prevents the formation of superoxide radicals, reduces the activity of enzymes of the lysosome.

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Due to the therapeutic effects of the active substance Dona normalizes the calcium deposits in bone and cartilage, to protect chondrocytes from the harmful effects of corticosteroids. The drug takes part in the course of normal metabolic processes in the formation of glycosaminoglycans in maintaining the elasticity of the cartilaginous tissue retains in its composition the water.

The drug improves the permeability of the joint capsule and restores enzymatic processes in the cells of cartilage tissue and synovial membrane. The drug is «don» rapidly and completely absorbed in the intestine. The drug freely penetrates the tissues, especially the cartilage of the joints.

Method of production and use of medicines

A medicine used for the treatment and prevention of osteoarthritis of various localization, therapy of humeroscapular periarthritis, chondromalacia of the patella. The drug is treatment of radiocarpal arthrosis, coxofemoral arthrosis, intervertebral osteochondrosis, knee arthrosis, spondylosis, treatment of arthrosis. After completion of the course of treatment the therapeutic effect lasts for 8 weeks.

Дона - лекарство от артроза: фармакологическое действие препаратаThe drug produces in two forms: powder and capsules. The powder is taken orally. In one sachet of powder contains 1500 mg of glucosamine sulfate. Staffed 20 sachets in a cardboard box. The package contains instructions for use.

The ampoules contain a solution for injection. The drug is administered intramuscularly. One ampoule contains 400 mg glucosamine sulfate. The package contains 6 vials of active substance and 6 vials of solvent. Prior to injection, the drug is mixed with a solvent.

Indications for the use of Dona are:

  • the primary deforming osteoarthritis;
  • secondary arthrosis of the joints;
  • osteochondrosis;
  • periarthritis of the hip.
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Дона - лекарство от артроза: фармакологическое действие препаратаThe powder is applied as follows. Need one sachet dissolve in 200 ml of water, taken once a day. The course of treatment lasts for 1,5-3 months. After that, the doctor prescribes a break for 2 months. Then repeat the treatment.

The drug in vials used for injections. The injections usually do 3 times a week. The course of treatment is 1-1,5 months. Sometimes combine the drug powder and injections. This comprehensive treatment gives better results.

Medicine can not be used if you are allergic to glucosamine, with severe cardiovascular disorders, epilepsy. Don is not assigned to a child younger than 12 years. Women in pregnancy or breastfeeding the drug is contraindicated.

This instruction is given for informational purposes. To self-medicate is impossible! All prescription medication performs doctor. In any case can not accept the remedy without the advice of a doctor! This may harm your health.

What side effects can cause drug

When therapy with this medicine may experience the following side reactions:

  • irritation of the skin;
  • allergies;
  • disorders of the digestive system;
  • nausea;
  • deterioration of the General condition;
  • dizziness;
  • disorders of the cardiovascular system;
  • the loss of orientation.

Analogue means in tablets is albona, as it is composed of glucosamine. Injections are considered the same rumalon and alflutop. However, to completely replace the don they can’t.

Patients who the doctor has prescribed remedy «the don», give a positive feedback about its effectiveness. The drug quickly relieves pain of joints, effective in combination with physiotherapy. Patients note that don is an excellent cure for osteoarthritis, it is very helpful in the treatment of early forms of arthritis and is very effective on stage 1-2. It restores the cartilage tissue of the patients of the joints, normalizes the formation of sufficient amounts of synovial fluid. When the disease a longer course is required to increase the drug.

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In stage 3 disease where the articular cartilage is almost completely destroyed, repair it very difficult. To grow new cartilage tissue and return to normal healthy shape of the deformed bones forming the joint, with only chondroprotectors impossible. In such patients, the doctor usually appoints surgical treatment that is more effective in such cases. And then require a long period of rehabilitation and comprehensive treatment, including physiotherapy, physiotherapy, medical support. While don take long, several courses with breaks.

The drug is «don» is one of the most effective chondroprotectors. It gives very good results of treatment, especially at the initial stage of osteoarthritis, almost completely restoring the healthy function of joint cartilage tissue.