Gout: treatment, tablets used during the attack
Such diseases as gout, is known to mankind since ancient times. The reason for its occurrence is to increase the level of uric acid in the blood. The excess uric acid leads to the fact that the kidneys do not have time to withdraw it from the body. The result is the deposition of salts in the joints which causes severe inflammation.
Successful treatment of the disease depends largely on the supply. From the diet should exclude all products that contribute to the formation of uric acid. Drug treatment of gout patient is prescribed when diet does not bring relief and uric acid level in the blood remains high.
Characteristics and symptoms of the disease
In the old days, gout was considered the disease of aristocrats, as it was developed as a result of excessive consumption of meat and alcohol, which the poor could not afford. Today, when meat and alcohol are available to almost all, the disease has covered almost all segments of the population. The prevalence of gout low: on the average on 1 thousand people there are only 3 cases, while men suffer from it more often than women.
Feature of the disease is that it is chronic and not fully cured. If a person was diagnosed with gout, it will need to prevent relapse until the end of life to stick to a special diet, eliminating from the diet of meat dishes and alcohol. Also very important, normal drinking regime. To the body’s output of uric acid, the patient should drink 2-2. 5 liters of fluid per day. But only if he does not suffer from kidney disease.
Gout is characterized by paroxysmal course. Its symptoms are difficult to confuse with any other disease. Gouty attack always starts suddenly and is accompanied by intolerable pain and increased sensitivity of the area around the joint, inside which the accumulated salts of uric acid. At the initial stage of the disease the pain is localized in the joint of the big toe. It gets hot and red.
The attack occurs most often at night when the person is at rest. If the patient does not pay attention to warning signs, do not go to a doctor and begin treatment, illness will progress and spread to other joints. The hallmark of gout are tophi (gouty lumps) generated at the place of accumulation of uric acid crystals. If the disease is run, it will lead to serious disturbances in the functioning of the kidneys.
Many people suffering from gout attacks, the question arises: how to treat this disease? Noticing the symptoms of the disease, the patient should contact the medical facility and get tested. If the result turns out that the level of uric acid in the blood is elevated, he will be assigned to treatment with medicines.
Drugs to treat gouty arthritis in modern medicine, not so much. They are divided into 2 groups:
- medications used by patients during an attack;
- tablets intended for long-term use in remission.
Drugs used during an attack
In the treatment of gout widely used anti-inflammatory and analgesic drug colchicine, which is aimed at normalizing uric acid metabolism in the body. Colchicine tablets intended for relief of acute attacks and in prophylactic means. It has on the body a complex effect:
- relieves pain;
- reduces the migration of leukocytes to site of inflammation;
- reduces the production of uric acid salts and prevents their accumulation in the joints.
Gout treatment with colchicine should be the initial stage of the attack, in this case the drug has on the patient maximum therapeutic effect. If pills gout make in the midst of the attack, they will not be able to relieve his symptoms. For the treatment of acute forms of gout on the legs and other inflamed areas, the colchicine should be taken only with the prescription of the doctor. Protivopodagricakih the duration of therapy is determined by the expert.
Before drinking colchicine should be familiar with contraindications to its use. These include:
- liver and kidney failure;
- advanced age;
- individual intolerance of the drug.
The most common side effects when treating drug are allergic reactions, abdominal pain, vomiting, diarrhea, anemia. Long-term use may cause the development of thrombocytopenia. 90% of patients say that the treatment of gouty arthritis with colchicine gives a positive therapeutic effect. Its analogues are tools such as colchicin and colhibin.
Today gout attacks successfully dealt with by nonsteroidal anti-inflammatory drugs (NSAIDs). These include phenylbutazone, indomethacin, indomethacin, ketazol, phenylbutazone and other drugs. Drugs from the group of NSAIDs effectively relieve pain in gouty attack, reduce temperature and reduce inflammation in affected joints. They are more effective than colchicine, and better tolerated by the patient. The question of which of non-steroid drugs it is best to choose should be decided by the doctor. He will prescribe the dosage of drugs and duration of its administration.
Since gout reminds himself always of a sudden, the patient is advisable to carry a doctor prescribed pills and in the event of an attack immediately to take them.
Drugs for prevention of exacerbations
If a person has chronic gout, its treatment is preventative drugs intended for long-term use. This drug is allopurinol — medication, the main effect of which is aimed at reducing the amount of uric acid in the body. Pills are available in dosages of 100 and 300 mg. For withdrawal seizures this medication is not administered, it is administered in the period of remission, when the patient joint is not inflamed.
Allopurinol dose the doctor selects for each patient individually, based on the results of his tests. The minimum dosage of the drug is 100 mg, maximum — 800 mg per day. In order to avoid the negative effects of gout treatment with allopurinol is initiated with minimal doses. Drinking cure is recommended after meals. To achieve a positive therapeutic effect of allopurinol should be taken over several months. Contraindications for the treatment of medical data means:
- pregnancy and lactation;
- kidney failure;
- individual intolerance to components of the medication.
Usually patients tolerate allopurinol, if you drink it. In rare cases, they may have side effects in the form of insomnia, depression, nausea, vomiting, diarrhea, blood disorders. At the initial stage of taking the drug may be an exacerbation of the disease due to release of uric acid from gouty tophi and other places of concentration. If you feel unwell while taking medications, the patient must consult a doctor.
In addition to allopurinol, protivopodagricescie drugs to lower uric acid levels are thiopurinol, probenecid, benzobromarone, anturan. They are also designed to prevent attacks of gout and are prescribed for a long period.