Osteogenic sarcoma of the jaw symptoms
Osteogenic sarcoma of the jaw, the symptoms early in the course of the disease does not cause much concern, since the cases look relatively healthy is of substandard craniofacial growth. With increased division of malignant cells of connective tissue, the periosteum, cortical bone and spongy bone marrow substance is formed and grows a tumor. Pain is experienced periodically, it is possible to stop drugs.
At first the symptoms resemble for colds, chronic fatigue. Sick self heals sinusitis, periodontal disease, trying to remove the swelling of the upper eyelid and bags under the eyes, sprinkles oral cavity refreshing liquid-to eliminate unpleasant smell, and when it comes to the doctor — the disease is often diagnosed in the later stages of development. Time for treatment is lost. The chances of a favorable outcome are greatly reduced.
The classic symptoms of the disease
Osteogenic sarcoma of the jaw refers to intractable malignant formations. For her, as for all diseases, typical weight loss, General weakness, irritability, poor sleep, reduced work capacity, loss of appetite, chronic fatigue, constant colds due to a weakened immune system. The patient increased lymph nodes, not only directly adjacent to the tumor, but also the entire lymphatic system of the body. However, similar symptoms have diseases not only cancer nature. Osteosarcoma of the jaw will manifest itself in a pain syndrome, edema, and violation of motor function of the temporomandibular joint.
At an early stage the cancer manifests itself as a dull ache only at night. With time the tumor grows, attracting in the process the surrounding tissue and increasing pain. When sarcoma penetrates into the lower jaw, the main location of the pain is teeth. In addition, as noted itching, rubefaction and irritation of the gums, teeth become loose and fall out. The jaw bone grows in volume by swelling of the soft tissues on the face is manifested spider veins are dilated small veins (called phlebectasia). In the jaw joint contracture develops, the amplitude of the movements decreases. If you palpate the problem area, the patient will feel a sharp pain, which gradually assumes a permanent character, becomes unbearable, does not sleep. Traditional analgesics do not provide analgesic effect.
During germination of the tumor into the surrounding tissue hampered outflow of fluid, which leads to the formation of stagnant lymph. Even with a small mass of malignant tumors in many cases, there is an external cosmetic defect in the form of a protrusion of soft tissue. In parallel, there is a so-called syndrome Vincent: tingling or numbness of the skin (at a later stage of the disease) in the middle of the lower lip and chin.
Marked restriction of mouth opening, the mandible moves to the side. When you increase the size sarcomere the formation of dense compression of the jaw occurs. Chewing food is difficult, the patient is difficult to talk.
At the initial stage of development of the disease the fever is not marked. Occasionally, the patient may record individual races (up to 38°C). Low-grade fever occurs 2-3 days and disappears on its own. In the last stages of the disease weakened body cannot remove from the body decay products of sarcoma, the temperature may rise to 40°C and does not subside for a long period. The result of the weakening of immunity of the patient may further be affected by infectious disease.
When malignant cancer cells grow inside the bone, in the nasal sinuses or eye sockets, it is called Central and peripheral anacleto first strikes soft tissue.
Symptoms also depend on the location of the tumor. If the neoplasm is located in the bones of the skull, external cosmetic defect and the pain will be with small size tumor. Osteosarcoma of the upper jaw entails a violation of the process of chewing food, the patient is difficult to open the mouth, jaw, reduced swelling of the soft tissues. Face emerges venous mesh, soft tissue of the face acquires the consistency of dough or clay. Documented cases of paresthesia and paresis of the muscles, since the nervous weave, Innervate the facial muscles and overall sensitivity are prevented.
Symptoms the location of the tumor in the upper jaw
In the early stages of the development of sarcoma of the upper jaw is often not recognized. Can be installed incorrectly, for example, sinologicheskoj diagnosis, since cancer is accompanied by bloody and purulent secretion from the nose. There is a sharp fetid smell from the mouth. The patient continues to breath through one nasal sinus or breathing through the mouth. The sense of smell disappears, fixed deformity with shift of the outer part of the nose in the opposite direction of the tumor. Attentive physician when performing rhinoscopy detect a tumor that will serve as the basis for the implementation of the biopsy.
Dentist during the inspection will note the dental signs of cancer:
- to some extent, hidden by gum tissue, do not end up slotted teeth;
- individual loosened teeth;
- pain in the area of the molars;
- oroantral ligament of the oral cavity and the maxillary sinus;
- the pathological limitation of masticatory muscles;
- unpleasant putrefactive smell.
Neurological symptoms — headache, neuralgia and pain syndromes in the area of the face.
If a sarcoma infiltrates in the ocular orbit, the eyeball changes its position, bulging to the side or forward (called exophthalmos), with pressure on the lacrimal duct is observed unintentional tearing. Swollen eyelids, visual acuity reduced. The eyeball can move and into the eye of the Department, then there is double vision — seeing objects forks. The growth of the malignancy is accompanied by intense and exhausting pain for all the branches of the trigeminal nerve, contracture of the masticatory muscles, and headache.
The facial skeleton undergoes changes, as the front wall of the maxillary sinus, alveolar bone and into the sky in front during the propagation process, the soft tissues are destroyed. On the face of the patient nasolabial furrow is smoothed, the face looks asymmetrical.
The bone structure of the upper jaw are injured even during a meal, which leads to the appearance of cracks and ulcers in the oral mucosa. To cancer joins secondary infection, which gives the additional complication of the disease. On the radiograph visible rounded metastasis and destruction of bone tissue, it blurred the boundaries of different diameter, periosteal visors.
Symptoms the location of the tumor in the lower jaw
Almost every time covers the teeth sarcoma of the mandible is illustrated, first of all, pain during jaw movements. Gives a sharp pain in the region innervated by inferior alveolar nerve. Often there is expansion of bone tissue because penetration of the tumour into the cancellous bone structure (bone swelling). After penetration of a malignant tumor deep bone formed unnatural bone cavity, teeth roots, located in the neighborhood, are in a state of ruin and degradation. The neck of each tooth is laid bare and bleeding, then the tooth becomes pathologically moving, loosened and falls out.
The mucosa of the oral cavity — alveolar ridge and the bottom of the mouth is covered with sores and cracks through which the weakened body get germs and infection. Therefore, osteogenic sarcoma, localized in the lower jaw is infiltration of tumor or ulcer. The subsequent spread of metastases in regional lymph nodes clinical picture of the disease is aggravated.
The growth of ekoobrazovanie annoying chin and mandibular nerves, the pain increases and becomes stronger. Gums also swells and deforms. Later on it is formed a slit-like ulcers full of pus. Of course, all this is accompanied by an unpleasant odor of decay. Alveolar bone is deformed. Malignancy erodes through the back wall, grows into cilobradine and temporal fossa, salivary glands under the jaw and around the ears.
Note the displacement of the tongue, larynx, pharyngeal wall in the middle section. Difficult speech and eating. The swelling that accompanies the disease gradually increases and leads to the asymmetry of the face. Soft facial tissue lose sensitivity.
With the collapse of sarcoma and concurrent infection of the body, the body temperature increased to 39.9°C, the pain progresses, covering the entire head area.
On the radiograph clearly visible rejection of the periosteum and formation of new bone pathological tissue: the individual spikes (spicules) and periosteal layering. The thickness of some parts of the jaw increases. If the bones of the lower jaw greatly affected, she may suddenly break.
Conclusion on the subject
Osteogenic sarcoma — a rare, very serious disease that requires immediate treatment. More likely to mention the upper-jaw localization — the defeat of the mandible is observed in approximately 30% of cases. However, if the malignancy is located in the lower jaw, it is more aggressive to the surrounding tissues, its rate of development is higher, flow faster apply onkokletki, forming metastases.