Tobrex drops and ointment for the eyes : manual, price, reviews, analogs

Тобрекс капли и мазь для глаз : инструкция, цена, отзывы, аналогиTobrex is an antibacterial agent used for the treatment of infectious eye diseases.

Belongs to the aminoglycoside antibiotics group. It has a wide spectrum of action. Effective against gram-positive (e.g., staphylococci) and gram-negative (e.g. Haemophilus coli, Pseudomonas aeruginosa, Klebsiella, etc.) bacteria.

The tool is almost not absorbed, so not able to exert systemic effects on the human body.

The composition and form of issue

The drug is presented to the drops and ointment for the eyes. Drops is a transparent solution that is placed into the vial-dropper, having a volume of 5 ml. Ointment is a plastic, viscous mass, is white in color and available in tubes. The main component of this drug is tobramycin. Drops additional substances are boric acid, benzalkonium chloride, anhydrous sodium sulfate, tyloxapol, sodium chloride, sulfuric acid, water. In ointments such substances are anhydrous chlorobutanol, white vaseline, liquid paraffin.

Indications for use

Тобрекс капли и мазь для глаз : инструкция, цена, отзывы, аналогиTobrex is used to treat inflammatory diseases of the visual organ and its surrounding tissues of an infectious nature:

  • of blepharitis;
  • iridocyclitis;
  • conjunctivitis;
  • of dacryocystitis;
  • keratoconjunctivitis;
  • blepharoconjunctivitis;
  • endophthalmitis;
  • nabomita.

The drug is also used prophylactically to prevent complications before and after operations on the eyes.

Method of application

Drops instilled into the eye every 4 hours for 1-2 drops. If the infection is acute, the procedure is repeated in an hour.

The interval between the drops increases with decreasing of the inflammatory process. Ointment lay a strip of 1.25 cm. behind the eyelid. The procedure is performed during the day 2-3 times. If the infection is acute, in 3-4 hours, lay a strip of 1.5 cm to obtain the desired effect, the dose is reduced to complete cessation of the use of materials.

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Tobrex available for both adults and children. Duration of therapy is for an adult 7-10 days, and for children – 7 days.


It is not recommended to use this tool for those people who have increased sensitivity to tobramycin. Only on prescription, the drug is used for children aged under 1 year, pregnant women, patients with impaired hearing or renal function.

Side effects

Тобрекс капли и мазь для глаз : инструкция, цена, отзывы, аналогиWhen using this medications possible side effects:

  • allergic reactions (redness, itching of the conjunctiva);
  • increased secretion of tears;
  • redness of the eyelids;
  • discomfort in the eye;
  • swelling of the conjunctiva;
  • inflammation of eyelid edges;
  • inflammatory processes in the cornea;
  • pain in the body;
  • ulceration of the cornea.

Also be aware that prolonged use of Tobrex may join in a fungal superinfection.


In overdose can occur following symptoms:

  • povyshennoe tears;
  • itching, redness and swelling of the eyelids;
  • point keratitis.

When using the drug topically in high doses, in the case of the described symptoms should rinse the eyes with clean water.

Interaction with other drugs

Tobrex is not recommended to use with drugs, which include tetracycline. Also, you cannot use this tool in conjunction with ethacrynic acid, cefamandole, cefuroxime, capreomycin, cefepime, vancomycin, with Cefotaxime because it may increase systemic side-effects (the appearance of ototoxic, nephrotoxic effects, failures in the mineral metabolism, etc.).

Special instructions

Тобрекс капли и мазь для глаз : инструкция, цена, отзывы, аналогиBefore using the ointment or drops should remove the lenses and wear them only in 15 minutes. It is not recommended to use the drug for a long time, since the high risk of fungal infection in the eye.

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If the drug is administered to a woman breastfeeding in the period of use drops or ointment Tobrex should stop breastfeeding.


Positive. Tobrex drops can be used for the treatment of infectious diseases of the eye for both adults and children. Buyers noted that the tool did a good job with such illnesses — dacryocystitis, conjunctivitis. It effectively eliminates the symptoms of the disease after a few days. When backfilling is not bad and does not burn the eyes.

Negative. It is an antibiotic and is not cheap.


Analogues of TOPEX are:

  • Tobrex 2X;
  • Nebcin;
  • Toby;
  • Bramitob;
  • Gentamicin;
  • Colbiocin;
  • Bilateral;
  • Cobrasoft;
  • Tobin;
  • Erythromycin.


In the Russian pharmacies price of Tobrex drops is from 190 to 220 rubles. The price of the ointment in the range of from 180 to 220 rubles.